Angle-resolved Optical Coherence Tomography with sequential angular selectivity for speckle reduction
Angle-resolved Optical Coherence Tomography with sequential angular selectivity for speckle reduction
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DOI：
10.1364/oe.15.006200
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发表时间：
2007-05-14
期刊：
影响因子：
3.8
通讯作者：
Bouma, B. E.
中科院分区：
文献类型：
--
作者：
Desjardins, A. E.;Vakoc, B. J.;Bouma, B. E.
提出了一种快速获取多后向散射角光学相干层析成像(OCT)图像的新方法。通过以角度合成这些图像，实现了高水平的斑点抑制。利用均匀的组织模型获得了3.4d B的信噪比改善，这与包含成像系统光学参数的散斑统计模型的预测很好地一致。此外，该系统的快速采集速率(10 kHzA线重复率)允许在体内进行角度合成，而不会出现明显的运动伪影。去除斑点的人体真皮OCT图像显示，组织微结构的描绘得到了极大的改善。(C)2006年美国光学学会。
We present a novel method for rapidly acquiring optical coherence tomography ( OCT) images at multiple backscattering angles. By angularly compounding these images, high levels of speckle reduction were achieved. Signal-to-noise ratio (SNR) improvements of 3.4 dB were obtained from a homogeneous tissue phantom, which was in good agreement with the predictions of a statistical model of speckle that incorporated the optical parameters of the imaging system. In addition, the fast acquisition rate of the system (10 kHz A-line repetition rate) allowed angular compounding to be performed in vivo without significant motion artifacts. Speckle-reduced OCT images of human dermis show greatly improved delineation of tissue microstructure. (C) 2006 Optical Society of America.