Irritable bowel syndrome in the United States: prevalence, symptom patterns and impact
Irritable bowel syndrome in the United States: prevalence, symptom patterns and impact
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DOI：
10.1111/j.1365-2036.2005.02463.x
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发表时间：
2005-06-01
影响因子：
7.6
通讯作者：
Barghout, V
中科院分区：
文献类型：
--
作者：
Hungin, APS;Chang, L;Barghout, V
背景：肠易激综合征（一种胃肠道运动障碍）的影响被低估且难以量化，因为临床医生可能只看到少数患者。目的：确定美国肠易激综合征的患病率、症状模式和影响。方法：这项两阶段社区调查采用配额抽样和随机数字电话拨号（筛选访谈）来识别经医学诊断为肠易激综合征的个体或未正式诊断但满足肠易激综合征的个体。肠综合征诊断标准（曼宁，罗马 I 或 II）。通过深入的后续访谈收集了有关肠易激综合症症状、一般健康状况、生活方式以及症状对个人生活的影响的信息。还收集了筛查访谈中确定的健康对照的数据。结果：5009 次筛查访谈中肠易激综合征的总患病率为 14.1%（医学诊断：3.3%；未确诊，但符合肠易激综合征标准：10.8%）。腹痛/不适是促使就诊的最常见症状。大多数患者（74% 经医学诊断；63% 未确诊）报告便秘和腹泻交替出现。先前诊断出的胃肠道疾病在患者中比非患者更常见。肠易激综合症患者比非患者有更多的休息天数（6.4 比 3.0）和卧床时间，并且活动减少程度更大。结论：美国大多数（76.6%）肠易激综合症患者未得到诊断。肠易激综合症对患者的福祉和健康有重大影响，并产生相当大的社会经济后果。
Background: The impact of irritable bowel syndrome, a gastrointestinal motility disorder, is underestimated and poorly quantified, as clinicians may see only a minority of sufferers.Aim: To determine the prevalence, symptom patterns and impact of irritable bowel syndrome in the US.Methods: This two-phase community survey used quota sampling and random-digit telephone dialling (screening interview) to identify individuals with medically diagnosed irritable bowel syndrome or individuals not formally diagnosed, but fulfilling irritable bowel syndrome diagnostic criteria (Manning, Rome I or II). Information on irritable bowel syndrome symptoms, general health status, lifestyle and impact of symptoms on individuals' lives was collected using in-depth follow-up interviews. Data were also collected for healthy controls identified in the screening interviews.Results: The total prevalence of irritable bowel syndrome in 5009 screening interviews was 14.1% (medically diagnosed: 3.3%; undiagnosed, but meeting irritable bowel syndrome criteria: 10.8%). Abdominal pain/discomfort was the most common symptom prompting consultation. Most sufferers (74% medically diagnosed; 63% undiagnosed) reported alternating constipation and diarrhoea. Previously diagnosed gastrointestinal disorders occurred more often in sufferers than non-sufferers. Irritable bowel syndrome sufferers had more days off work (6.4 vs. 3.0) and days in bed, and reduced activities to a greater extent than non-sufferers.Conclusions: Most (76.6%) irritable bowel syndrome sufferers in the US are undiagnosed. Irritable bowel syndrome has a substantial impact on sufferers' well-being and health, with considerable socioeconomic consequences.