Diversity-Oriented Approach to Carbocycles and Heterocycles through Ring-Rearrangement Metathesis, Fischer Indole Cyclization, and Diels-Alder Reaction as Key Steps
Diversity-Oriented Approach to Carbocycles and Heterocycles through Ring-Rearrangement Metathesis, Fischer Indole Cyclization, and Diels-Alder Reaction as Key Steps
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DOI：
10.1002/ejoc.201402273
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发表时间：
2014-09-01
影响因子：
2.8
通讯作者：
Ravikumar, Ongolu
中科院分区：
文献类型：
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作者：
Kotha, Sambasivarao;Ravikumar, Ongolu
在钌催化剂的存在下，对容易获得的二环戊二烯衍生物进行环重排复分解，以提供一系列含有碳环、氧杂环和氮杂环的稠合多环框架。我们已经使用原子经济的过程，如环重排复分解，Fischer吲哚环化，和Diels-Alder反应作为关键步骤。
Readily available dicyclopentadiene derivatives were subjected to ring-rearrangement metathesis in the presence of ruthenium catalysts to deliver a range of fused polycycle frameworks containing carbocycles, oxacycles, and azacycles. We have used atom-economic processes such as ring-rearrangement metathesis, Fischer indole cyclization, and the Diels-Alder reaction as key steps.