Distress in Older Patients With Cancer
Distress in Older Patients With Cancer
复制标题
DOI：
10.1200/jco.2008.19.9463
复制
发表时间：
2009-09-10
影响因子：
45.3
通讯作者：
Kelly, Eva
中科院分区：
文献类型：
--
作者：
Hurria, Arti;Li, Daneng;Kelly, Eva
PurposeTo determine the predictors of distress in older patients with cancer.Patients and MethodsPatients age >= 65 years with a solid tumor or or lymphoma completed a questionnaire that addressed these geriatric assessment domains：functional status，comorbidity，psychological state，nutritional status，and social support.患者使用一种名为“痛苦温度计”的有效筛选工具，在0到10的范围内自我评估他们的痛苦程度。苦恼和老年评估scores之间的关系examined.ResultsThe老年评估问卷完成了245例（平均年龄，76岁;标准差[SD]，7年;范围，65至95岁）与癌症（36%的IV期; 71%的女性）。其中，87%的人还完成了痛苦温度计，41%（n = 87）的人报告了0至10分（平均分，3; SD，3;范围，0至10）的痛苦评分>= 4。双变量分析表明，较高的痛苦（>= 4）和较差的身体功能，增加共病的医疗条件，视力差，无法单独完成问卷，并需要更多的时间来完成问卷之间的关联。在一个多变量回归模型的基础上显着的双变量的结果，较差的身体功能（增加需要协助工具的日常生活活动[P = 0.015]和较低的身体功能评分的医疗结果调查[P = 0.018]）显着相关的较高的痛苦scores.ConclusionSignificant困扰确定在41%的老年癌症患者。产后身体功能是最好的预测痛苦。需要进一步的研究来确定改善或帮助身体功能的干预措施是否有助于减少老年癌症患者的痛苦。
PurposeTo determine the predictors of distress in older patients with cancer.Patients and MethodsPatients age >= 65 years with a solid tumor or lymphoma completed a questionnaire that addressed these geriatric assessment domains: functional status, comorbidity, psychological state, nutritional status, and social support. Patients self-rated their level of distress on a scale of zero to 10 using a validated screening tool called the Distress Thermometer. The relationship between distress and geriatric assessment scores was examined.ResultsThe geriatric assessment questionnaire was completed by 245 patients (mean age, 76 years; standard deviation [SD],7 years; range, 65 to 95 years) with cancer (36% stage IV; 71% female). Of these, 87% also completed the Distress Thermometer, with 41% (n = 87) reporting a distress score of >= 4 on a scale of zero to 10 (mean score, 3; SD, 3; range, zero to 10). Bivariate analyses demonstrated an association between higher distress (>= 4) and poorer physical function, increased comorbid medical conditions, poor eyesight, inability to complete the questionnaire alone, and requiring more time to complete the questionnaire. In a multivariate regression model based on the significant bivariate findings, poorer physical function (increased need for assistance with instrumental activities of daily living [P = .015] and lower physical function score on the Medical Outcomes Survey [P = .018]) correlated significantly with a higher distress score.ConclusionSignificant distress was identified in 41% of older patients with cancer. Poorer physical function was the best predictor of distress. Further studies are needed to determine whether interventions that improve or assist with physical functioning can help to decrease distress in older adults with cancer.