Genomic application in sheep and goat breeding
Genomic application in sheep and goat breeding
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DOI：
10.2527/af.2016-0006
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发表时间：
2016-01-01
期刊：
影响因子：
3.6
通讯作者：
Conington, Joanne
中科院分区：
文献类型：
--
作者：
Rupp, Rachel;Mucha, Sebastian;Conington, Joanne
2009年，随着50K羊SNP芯片的开发，小型反刍动物的基因组研究首次成为可能。基因组评估现已在新西兰和澳大利亚的绵羊、法国的奶羊以及法国和英国的山羊中实施。这些物种基因组选择的具体问题包括：参考种群规模小，连锁不平衡程度低，多品种评估，许多国家缺乏表型记录，以及历史基因分型成本的边际成本效益。快速降低基因分型成本，再加上更好地理解如何最大化基因组选择的好处，意味着采用基因分型技术的人数将急剧上升。
Genomic studies in small ruminants were first possible in 2009 with the development of the 50K ovine SNP chip.Genomic evaluation has now been implemented in sheep in New Zealand and Australia, dairy sheep in France, and in goats in France and the UK.Specific issues of genomic selection for these species include: small reference population sizes, low linkage disequilibrium, multi-breed evaluations, lack of phenotype recording in many countries, and marginal cost-benefit at historic genotyping costs.Rapidly reducing genotyping cost coupled with a better understanding of how to maximize benefits of genomic selection mean adoption is poised to rise dramatically.