Regioselective hydronickelation of allenes and its application to the hydrocyanative carbocyclization reaction of allene-ynes and bis-allenes.
Regioselective hydronickelation of allenes and its application to the hydrocyanative carbocyclization reaction of allene-ynes and bis-allenes.
复制标题
丙二烯的区域选择性氢化镍及其在丙二烯-炔和双-丙二烯氢氰化碳环化反应中的应用。
DOI：
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发表时间：
2013
影响因子：
3.6
通讯作者：
A. Nishida
中科院分区：
文献类型：
--
作者：
Yuka Amako;H. Hori;S. Arai;A. Nishida
研究了镍催化下烯丙烷和双烯丙烷的碳氰化环化反应。关键步骤是烯烃的区域选择性氢化镍反应和随后的碳金属化环化反应。前者决定反应路径，后者控制取代烯烃的立体化学。这些产品是有用的碳环和杂环，包括氰基、官能化双键和季碳。
The carbocyanative cyclization of allene-ynes and bis-allenes under nickel catalysis is described. The key steps are the regioselective hydronickelation of allenes and subsequent cyclization via carbometalation. The former step determines the reaction pathway, and the latter controls the stereochemistry of substituted olefins. The products are useful carbo- and heterocycles that include a cyano group, functionalized double bonds, and quaternary carbons.
影响因子：
5.2
作者：
J. Keith;E. Jacobsen
通讯作者：
J. Keith;E. Jacobsen