The effects of cystoscopy and hydrodistention on symptoms and bladder capacity in interstitial cystitis/bladder pain syndrome.
The effects of cystoscopy and hydrodistention on symptoms and bladder capacity in interstitial cystitis/bladder pain syndrome.
复制标题
膀胱镜检查和水扩张对间质性膀胱炎/膀胱疼痛综合征症状和膀胱容量的影响。
DOI：
10.1002/nau.23555
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发表时间：
2018
影响因子：
2
通讯作者：
Cameron,AnneP
中科院分区：
文献类型：
--
作者：
Kirk,PeterS;Santiago-Lastra,Yahir;Qin,Yongmei;Stoffel,JohnT;Clemens,JamesQ;Cameron,AnneP
目的膀胱镜检查和膀胱水扩张在间质性膀胱炎/膀胱疼痛综合征（IC/BPS）治疗中的应用在不同的医生之间有很大的差异。目前关于水扩张的风险和益处以及反复水扩张的长期影响的证据还没有很好地建立。我们试图描述水扩张对IC/BPS症状以及膀胱容量的影响。MethodsWe回顾性地查询了我们的机构记录，这些患者患有非溃疡性IC/BPS，在11年的时间内接受水扩张，以获得诊断和治疗时的人口统计学和临床因素。症状缓解和膀胱容量的变化进行了评估，和多变量模型被用来预测responsibility.ResultsThere是328例患者进行hydrodilation在研究期间，其中36%的程序多次，和整体中位数随访38.6个月。反复水扩张的患者更可能是女性，有更多的共病疼痛障碍，并尝试过抗胆碱能药物和膀胱内滴注。未观察到平均膀胱容量随时间推移而降低（P= 0.40）。症状评分显着下降，观察程序后，在多个questionnaire. ConclusionsHydrodilation不降低膀胱容量，即使与多个程序，并可测量改善症状，在一些患者IC/BPS。继续努力，以更好地确定那些患者最有可能受益于这一程序是合理的。
AimsThe use of cystoscopy and hydrodistention in the management of interstitial cystitis/bladder pain syndrome (IC/BPS) varies widely between providers. Current evidence regarding the risks and benefits of hydrodistention, as well as the long term effects of repeated hydrodistention are not well established. We sought to characterize the effects of hydrodistention on IC/BPS symptoms as well as bladder capacity.MethodsWe retrospectively queried our institutional records for patients with non‐ulcerative IC/BPS who underwent hydrodistention over an 11‐year period to obtain demographic and clinical factors at the time of diagnosis and treatment. Symptom relief and bladder capacity changes were assessed, and multivariable models were used to predict response to treatment.ResultsThere were 328 patients who underwent hydrodistention during the study period, of whom 36% received the procedure multiple times, and overall median follow‐up was 38.6 months. Patients with repeated hydrodistentions were more likely to be female, have more comorbid pain disorders, and have trialed anticholinergic medications and intravesical instillations. No decrease in mean bladder capacity was observed over time (P= 0.40). Significant decreases in symptom scores were observed following the procedure on multiple questionnaires.ConclusionsHydrodistention does not decrease bladder capacity even with multiple procedures, and measurably improves symptoms in some patients with IC/BPS. Continuing efforts to better identify those patients most likely to benefit from this procedure are justified.