Pilot Study of the Effect of Ultraviolet Light on Pain and Mood in Fibromyalgia Syndrome
Pilot Study of the Effect of Ultraviolet Light on Pain and Mood in Fibromyalgia Syndrome
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DOI：
10.1089/acm.2008.0167
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发表时间：
2009-01-01
影响因子：
2.6
通讯作者：
Feldman, Steven R.
中科院分区：
文献类型：
--
作者：
Taylor, Sarah L.;Kaur, Mandeep;Feldman, Steven R.
背景：纤维肌痛综合征（FMS）相关疼痛缺乏有效的系统性或充分的对症治疗。坊间传闻紫外线（UV）可能有一些好处。目的：本研究的目的是确定UV是否有效地改善FMS患者的慢性疼痛。方法：19名FMS受试者加入紫外线和非紫外线（对照）晒黑床的对照试验，为期2周，然后随机分组，接受紫外线或非紫外线（对照）照射，再持续6周。最后一次治疗后4周随访。采用11分数值疼痛评分（Likert量表）、视觉模拟疼痛量表（VAS）和McGill疼痛问卷来评估疼痛。情绪变量也被评估。结果：在受试者接受紫外线和非紫外线（对照）暴露的最初2周内，暴露于紫外线后的11分李克特疼痛评分比暴露前水平下降0.44分（标准差= 0.095）。此外，与非紫外线（对照）暴露相比，紫外线暴露会产生更大的积极影响、幸福感、放松和疼痛水平降低（优势比[OR] = 2.80, p = 0.0059）。随机治疗期后，根据McGill疼痛问卷测量，紫外线组与非紫外线组相比疼痛有轻微改善（12.2 vs 14.1, p = 0.049）；其他疼痛量表的结果不显著。最后一次治疗后4周的评估显示，在调整后的结果平均得分上没有显著差异。结论：这项初步研究的结果表明，晒黑床可能在减轻FMS患者疼痛方面具有一定的潜力。
Background: There is a lack of effective systemic or adequate symptomatic treatment for pain associated with fibromyalgia syndrome (FMS). Anecdotes suggest ultraviolet (UV) light may be of some benefit.Purpose: The purpose of the present study was to determine if UV is effective in ameliorating chronic pain in persons with FMS.Methods: Nineteen subjects with FMS were enrolled in a controlled trial of UV and non-UV (control) tanning beds for 2 weeks, followed by randomization to receive UV or non-UV (control) exposure for 6 additional weeks. A follow-up interview was conducted 4 weeks after the last treatment. Pain was assessed with an 11-point numerical pain rating (Likert scale), a visual analogue pain scale (VAS), and the McGill Pain Questionnaire. Mood variables were also assessed.Results: During the initial 2 weeks when subjects received both UV and non-UV (control) exposures, the 11-point Likert scale pain score decreased 0.44 points after exposure to UV from pre-exposure levels (S. E. = .095). Additionally, UV exposure resulted in greater positive affect, well-being, relaxation, and reduced pain levels when compared to non-UV (control) exposure (Odds Ratio [OR] = 2.80, p = 0.0059). Following the randomized treatment period, there was slight improvement in pain as measured by the McGill Pain Questionnaire in the UV group compared to the non-UV (control) group (12.2 versus 14.1; p = 0.049); the other pain scales yielded nonsignificant results. Assessment 4 weeks after the last treatment showed no significant differences in scores in the adjusted means for outcomes.Conclusions: Results from this pilot study suggest that tanning beds may have some potential in reducing pain in persons with FMS.