Anticipatory changes in beta synchrony in the human corticospinal system and associated improvements in task performance
Anticipatory changes in beta synchrony in the human corticospinal system and associated improvements in task performance
复制标题
DOI：
10.1111/j.1460-9568.2007.05620.x
复制
发表时间：
2007-06-01
影响因子：
3.4
通讯作者：
Brown, Peter
中科院分区：
文献类型：
--
作者：
Androulidakis, Alexandros G.;Doyle, Louise M. F.;Brown, Peter
在健康人的大脑运动皮层中，可以以皮质肌相干的形式检测到β频带（13-30 Hz）中的同步振荡活动。β活性升高与新运动的处理受损以及更有效的姿势或强直性收缩相关。因此，在自主运动之前，β活动被抑制，之后在面对外周情感时反弹。然而，它仍然有待确定是否在β带的同步活动可以上调的任务适当的方式独立的混淆变化的感觉传入。在这里，我们表明，有一个系统的和前瞻性的增加β同步之前，预期的姿势挑战。这种β同步性的上调与行为表现的改善有关。我们指导9名健康的受试者执行食指的反应时间运动，以响应命令性视觉提示或抵抗向同一方向拉伸手指。这些事件之前，一致的和不太常见的不一致的警告线索。当受试者被警告即将拉伸时，β同步性暂时增加，而当警告提示即将到来的反应时间任务时，β同步性下降。手指的位置不太成功地保持在面对拉伸和反应时间较长时，警告线索是不一致的。结果表明，β状态是调制在一个任务相关的方式与伴随的行为后果。
Synchronized oscillatory activity in the beta frequency band (13-30 Hz) can be detected in the cerebral motor cortex of healthy humans in the form of corticomuscular coherence. Elevated beta activity is associated with impaired processing of new movements and with more efficient postural or tonic contraction. Accordingly, beta activity is suppressed prior to voluntary movements, rebounding thereafter in the face of peripheral afferance. However, it remains to be established whether synchronized activity in the beta band can be up-regulated in a task-appropriate way independently of confounding changes in sensory afferance. Here we show that there is a systematic and prospective increase in beta synchrony prior to an expected postural challenge. This up-regulation of beta synchrony is associated with improved behavioural performance. We instructed nine healthy subjects to perform a reaction-time movement of the index finger in response to an imperative visual cue or to resist a stretch to the finger in the same direction. These events were preceded by congruent and less common incongruent warning cues. Beta synchrony was temporally increased when subjects were warned of an impending stretch and decreased following a warning cue signalling a forthcoming reaction-time task. Finger positions were less successfully maintained in the face of stretches and reaction times were longer when warning cues were incongruent. The results suggest that the beta state is modulated in a task-relevant way with accompanying behavioural consequences.