The Los Angeles Latino eye study - Design, methods, and baseline data
The Los Angeles Latino eye study - Design, methods, and baseline data
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DOI：
10.1016/j.ophtha.2004.02.001
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发表时间：
2004-06-01
期刊：
影响因子：
13.7
通讯作者：
Preston-Martin, S
中科院分区：
文献类型：
--
作者：
Varma, R;Paz, SH;Preston-Martin, S
目的：描述洛杉矶拉丁美洲人眼科研究（LALES）的研究设计、操作策略、程序和基线特征。LALES是一项基于人群的评估拉丁美洲人视力损害、眼部疾病和视觉功能的患病率的研究。设计：基于人群的横断面研究。参与者：来自加州洛杉矶6个人口普查区的6，357名40岁及以上的拉丁裔人。方法：对每位符合条件的参与者进行详细的采访和眼部检查。访谈包括人口统计学、行为和眼部危险因素以及健康相关和视力相关生活质量的评估。眼部检查包括测量视力、眼内压和视野;眼底和视盘摄影;详细的前节和后节检查;以及测量血压、糖化血红蛋白水平和血糖水平。主要结局指标：视力损害、失明、白内障、青光眼、糖尿病视网膜病变和年龄相关性黄斑变性的患病率构成了研究的主要结果变量。次要结果包括与眼病相关的危险因素的比值比、健康相关的生活质量和视力相关的生活质量。应答率和基线特征presented.Results：7789个人符合LALES，6357（82%）有临床检查，另外524只完成了在家里的采访。大多数参与者为女性（58%），平均（+/-标准差）年龄为54.9（+/-10.8）岁，80.0%为墨西哥裔，0.4%自认为是美洲印第安人或阿拉斯加原住民。LALES参与者的年龄分布是相似的，墨西哥裔的拉丁美洲人在美国的其他地区。结论：LALES招募了拉丁美洲人40岁及以上的眼科流行病学研究。LALES队列将提供关于美国最大和增长最快的少数民族眼病患病率和风险因素的信息。(C)2004年，美国眼科学会。
Objective: To describe the study design, operational strategies, procedures, and baseline characteristics of the Los Angeles Latino Eye Study (LALES), a population-based assessment of the prevalence of visual impairment, ocular disease, and visual functioning in Latinos.Design: Population-based, cross-sectional study.Participants: Six thousand three hundred fifty-seven Latinos 40 years and older from 6 census tracts in Los Angeles, California.Methods: A detailed interview and eye examination were performed on each eligible participant. The interview included an assessment of demographic, behavioral, and ocular risk factors and health-related and vision-related quality of life. The eye examination included a measurement of visual acuity, intraocular pressure, and visual fields; fundus and optic disc photography; a detailed anterior and posterior segment examination; and measurement of blood pressure, glycosylated hemoglobin levels, and blood glucose levels. Main Outcome Measures: Prevalence of visual impairment, blindness, cataract, glaucoma, diabetic retinopathy, and age-related macular degeneration constitute the study's primary outcome variables. Secondary outcomes include odds ratios for risk factors associated with eye disease, health-related quality of life, and vision-related quality of life. Response rates and baseline characteristics are presented.Results: Of the 7789 individuals eligible for LALES, 6357 (82%) had a clinical examination; an additional 524 completed only an in-home interview. The majority of participants were female (58%), the average (+/-standard deviation) age was 54.9 (+/-10.8) years, and 80.0% were of Mexican origin and 0.4% self-identified as American Indian or Alaskan Native. The age distribution of LALES participants was similar to that of Latinos of Mexican origin in the rest of the United States.Conclusion: The LALES has recruited Latinos 40 and older for an ophthalmic epidemiologic study. The LALES cohort will provide information about the prevalence and risk factors of ocular disease in the largest and fastest growing minority in the United States. (C) 2004 by the American Academy of Ophthalmology.