Molecular weight of human gamma interferon is similar to that of other human interferons.
Molecular weight of human gamma interferon is similar to that of other human interferons.
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DOI：
10.1126/science.6173921
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发表时间：
1982-01
期刊：
影响因子：
56.9
通讯作者：
Y. Yip;B. Barrowclough;C. Urban;J. Vilček
中科院分区：
文献类型：
--
作者：
Y. Yip;B. Barrowclough;C. Urban;J. Vilček
人γ干扰素（以前称为免疫或II型干扰素）的分子量（通过分子筛色谱法测定）在40，000和70，000之间。在十二烷基硫酸钠-聚丙烯酰胺凝胶电泳上，γ干扰素活性主要从对应于分子量为20，000和25，000的凝胶的两个区域恢复。结果表明，在天然形式的人γ干扰素可以聚集。
The molecular weight (as determined by molecular sieve chromatography) of human gamma interferon, formerly referred to as immune or type II interferon, is between 40,000 and 70,000. On sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gamma interferon activity was recovered mainly from two regions of the gels corresponding to molecular weights of 20,000 and 25,000. The results suggest that in native form human gamma interferon may be aggregated.