Apraxia of Eyelid Opening: Clinical Features and Therapy
Apraxia of Eyelid Opening: Clinical Features and Therapy
复制标题
眼睑张开失用症：临床特征和治疗
DOI：
10.1177/112067210601600202
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发表时间：
2006
影响因子：
1.7
通讯作者：
K. Eidal
中科院分区：
文献类型：
--
作者：
E. Kerty;K. Eidal
目的肉毒毒素注射是治疗良性特发性眼睑痉挛的首选方法。然而，约10%的患者从这种治疗中得不到足够的效果，其中许多患者还伴有开盖失用。方法对12例患者进行为期3年的治疗。其中3例为单纯翻盖失用，9例合并眼睑痉挛。所有患者最初都接受了肉毒杆菌毒素注射治疗，但效果不佳。他们接受了手术治疗，如眼睑成形术，有限的肌肉切除，腱膜修复，和/或额肌悬吊术。部分患者术后需要在眼轮匝肌的颧前部注射肉毒杆菌毒素。结果该综合疗法具有良好的功能和美容效果。结论眼睑痉挛和翻盖失用的具体原因尚不清楚，但这两种情况在部分患者中并存，治疗难度较大。做出正确的诊断是很重要的，手术和肉毒杆菌毒素的联合治疗可以非常有效。
Purpose Botulinum toxin injection is the treatment of choice in cases of benign essential blepharospasm. However, about 10% of the patients do not get sufficient effect from this treatment, and many of them have concomitant apraxia of lid opening. Methods Over a 3-year period we treated 12 patients. Three had pure apraxia of lid opening and in the other nine it was associated with blepharospasm. All patients were initially treated with botulinum toxin injections with poor results. They underwent surgical treatment like blepharoplasty limited myectomy, aponeurosis repair, and/or frontalis suspension. Some of them needed postoperative botulinum toxin injections in the pretarsal part of orbicularis oculi muscles. Results This combined therapy gave good functional and aesthetic results. Conclusions The specific causes of blepharospasm and apraxia of lid opening are unknown, but these two conditions coexist in some patients and can be difficult to treat. It is important to make a correct diagnosis, and a combined surgical and botulinum toxin treatment can be very effective.