A Plan for Academic Biobank Solvency-Leveraging Resources and Applying Business Processes to Improve Sustainability.
A Plan for Academic Biobank Solvency-Leveraging Resources and Applying Business Processes to Improve Sustainability.
复制标题
学术生物库偿付能力计划——利用资源并应用业务流程来提高可持续性。
DOI：
10.1111/cts.12287
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Short,Nancy
中科院分区：
文献类型：
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作者：
Uzarski,Diane;Burke,James;Turner,Barbara;Vroom,James;Short,Nancy
基于学术机构的研究人员发起的生物库为医学贡献了宝贵的生物标志物和转化研究进展。由于许多传统银行曾经得到联邦资金的支持，财政支持的减少威胁到现有和新生物银行的未来。当杜克大学布莱恩阿尔茨海默病中心（ADRC）的脑库面临资金危机时，一个协作的多学科团队开始了一个为期2年的生物库可持续性项目，该项目利用全面的业务战略，专门的项目管理和涉及许多杜克大学实体的系统方法。通过综合和应用现有知识，杜克转化医学研究所创建并推出了一种商业模式，可以调整并应用于传统和初创的学术生物库。这种模式为确定新的供资机制提供了一条途径，同时也强调改善沟通、业务发展，并注重与行业合作，以改善生物标本的获取。已成功达到短期人才库稳定的基准，并正在评估长期可持续性指标。
Researcher‐initiated biobanks based at academic institutions contribute valuable biomarker and translational research advances to medicine. With many legacy banks once supported by federal funding, reductions in fiscal support threaten the future of existing and new biobanks. When the Brain Bank at Duke University's Bryan Alzheimer's Disease Center (ADRC) faced a funding crisis, a collaborative, multidisciplinary team embarked on a 2‐year biobank sustainability project utilizing a comprehensive business strategy, dedicated project management, and a systems approach involving many Duke University entities. By synthesizing and applying existing knowledge, Duke Translational Medicine Institute created and launched a business model that can be adjusted and applied to legacy and start‐up academic biobanks. This model provides a path to identify new funding mechanisms, while also emphasizing improved communication, business development, and a focus on collaborating with industry to improve access to biospecimens. Benchmarks for short‐term Brain Bank stabilization have been successfully attained, and the evaluation of long‐term sustainability metrics is ongoing.