Self-assembled nanoparticle arrays for multiphase trace analyte detection
Self-assembled nanoparticle arrays for multiphase trace analyte detection
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DOI：
10.1038/nmat3488
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发表时间：
2013-02-01
期刊：
影响因子：
41.2
通讯作者：
Edel, Joshua B.
中科院分区：
文献类型：
--
作者：
Cecchini, Michael P.;Turek, Vladimir A.;Edel, Joshua B.
为利用表面增强拉曼光谱检测痕量分析物而设计的纳米等离子体结构通常需要复杂的纳米制造技术。制备这种衬底的另一种选择是依靠纳米颗粒在液/液或液/气界面上自组装成紧密堆积的阵列。阵列的密度可以通过改变纳米颗粒的官能度、溶液的pH值和盐的浓度来控制。重要的是，这些阵列是坚固的、自我修复的、可重复性的，并且非常易于操作。在这里，我们报告了利用由金纳米颗粒形成的这种平台来检测来自水、有机或空气相的多分析物。在我们的系统中，Au阵列的界面面积约为25 mm(2)，并且可以制作得更小，使该平台成为小体积、低浓度和痕量分析物的理想平台。重要的是，易于组装和快速检测使该平台成为毒素、爆炸物、毒品或其他危险化学品现场样品检测的理想选择。
Nanoplasmonic structures designed for trace analyte detection using surface-enhanced Raman spectroscopy typically require sophisticated nanofabrication techniques. An alternative to fabricating such substrates is to rely on self-assembly of nanoparticles into close-packed arrays at liquid/liquid or liquid/air interfaces. The density of the arrays can be controlled by modifying the nanoparticle functionality, pH of the solution and salt concentration. Importantly, these arrays are robust, self-healing, reproducible and extremely easy to handle. Here, we report on the use of such platforms formed by Au nanoparticles for the detection of multi-analytes from the aqueous, organic or air phases. The interfacial area of the Au array in our system is approximate to 25 mm(2) and can be made smaller, making this platform ideal for small-volume samples, low concentrations and trace analytes. Importantly, the ease of assembly and rapid detection make this platform ideal for in-the-field sample testing of toxins, explosives, narcotics or other hazardous chemicals.