Molecular Commerce on Coral Reefs: Using Metabolomics to Reveal Biochemical Exchanges Underlying Holobiont Biology and the Ecology of Coastal Ecosystems
Molecular Commerce on Coral Reefs: Using Metabolomics to Reveal Biochemical Exchanges Underlying Holobiont Biology and the Ecology of Coastal Ecosystems
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DOI：
10.3389/fmars.2021.630799
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发表时间：
2021-07-23
影响因子：
3.7
通讯作者：
Haas, Andreas F.
中科院分区：
文献类型：
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作者：
Kelly, Linda Wegley;Nelson, Craig E.;Haas, Andreas F.
快速发展的代谢组学领域包括一套强大的分析和生物信息学工具，可以帮助揭示单个生物体，物种相互作用和整个生态系统中化合物的多样性和活性。从这个角度来看，我们使用珊瑚礁研究的例子来说明代谢组学已经并可以应用于了解沿海生态系统的方式。代谢组学可以提供的新见解的例子包括解决植物，动物及其微生物群之间的代谢物交换，确定与不同微生物互利关系的发生和维持相关的代谢物交换，这些微生物互利关系表征在珊瑚中充当线索的未知分子，繁殖，或定义参与珊瑚-藻类竞争的化合物套件和藻类占主导地位的生态系统的微生物化。在这里，我们概述了海洋生物学家和生态学家可以应用的采样，分析和信息学方法，以了解化学过程在生态系统中的作用，重点是开放获取数据分析工作流程和民主化数据库。最后，我们展示了这些代谢组学工具和生物信息学方法如何为科学家提供绘制详细代谢清单和动态的机会，以便全面了解珊瑚礁生物，共生体及其周围海洋环境之间的关系。
The rapidly advancing field of metabolomics encompasses a diverse suite of powerful analytical and bioinformatic tools that can help to reveal the diversity and activity of chemical compounds in individual organisms, species interactions, and entire ecosystems. In this perspective we use examples from studies of coral reefs to illustrate ways in which metabolomics has been and can be applied to understand coastal ecosystems. Examples of new insights that can be provided by metabolomics include resolving metabolite exchange between plants, animals and their microbiota, identifying the relevant metabolite exchanges associated with the onset and maintenance of diverse, microbial mutualisms characterizing unknown molecules that act as cues in coral, reproduction, or defining the suites of compounds involved in coral-algal competition and microbialization of algal-dominated ecosystems. Here we outline sampling, analytical and informatic methods that marine biologists and ecologists can apply to understand the role of chemical processes in ecosystems, with a focus on open access data analysis workflows and democratized databases. Finally, we demonstrate how these metabolomics tools and bioinformatics approaches can provide scientists the opportunity to map detailed metabolic inventories and dynamics for a holistic view of the relationships among reef organisms, their symbionts and their surrounding marine environment.