Tuberculosis of Larynx Revisited: a Report on Clinical Characteristics in 10 Cases
Tuberculosis of Larynx Revisited: a Report on Clinical Characteristics in 10 Cases
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DOI：
10.1007/s12070-011-0333-4
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发表时间：
2012-09-01
影响因子：
0.6
通讯作者：
Thekedar, Pallavi
中科院分区：
文献类型：
--
作者：
Gandhi, Sachin;Kulkarni, Santosh;Thekedar, Pallavi
结核是最常见的肉芽肿性喉部疾病。在大多数情况下，它是继发于肺结核。由于免疫缺陷状态的发病率增加，结核病的发病率现在正在上升。在此，我们根据10例喉结的临床特点报告。在我们的三级护理喉科中心对10例喉结核患者进行了详细的回顾性分析。多数患者有声音改变和干咳。所有患者均出现声带充血、水肿。80%的患者累及杓状肌和会厌皱襞。70%的患者可见弗兰克性肉芽肿生长。所有患者的组织病理学报告均符合结核性肉芽肿。2例合并肺结核。8例患者未发现任何提示既往或合并肺结核的特征。所有患者对化疗均有完全缓解的反应。原发性喉部结核并不像一般认为的那么罕见。本丛书提供了对喉部结核的临床特征、生长模式和治疗的见解。
Tuberculosis is the most frequent granulomatous disease involving larynx. In most cases it is secondary to pulmonary tuberculosis. Incidence of tuberculosis is now on a rise due to increase in incidence of immune deficiency states. Here we present a report of clinical characteristic of laryngeal tuberculosis based on our experience of 10 cases. A detailed retrospective analysis of 10 patients of laryngeal tuberculosis was done at our tertiary care laryngology centre. Majority of patients had change of voice and dry cough. All the patients had hyperemia and edema of vocal cords. 80% patients had involvement of the arytenoids and ary-epiglottic folds. Frank granulomatous growth was seen in 70% of patients. In all patients histopathological report was consistent with tubercular granuloma. Two patients had associated pulmonary tuberculosis. Eight patients did not reveal any feature suggestive of previous or co-existent pulmonary tuberculosis. All patients responded to chemotherapy with complete resolution. Primary laryngeal tuberculosis is not as rare as generally considered. This series provides an insight towards clinical feature, growth pattern and management of tuberculosis of larynx.