Feasibility Studies of a New Event Selection Method to Improve Spatial Resolution of Compton Imaging for Medical Applications.
Feasibility Studies of a New Event Selection Method to Improve Spatial Resolution of Compton Imaging for Medical Applications.
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DOI：
10.1109/trpms.2017.2703095
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发表时间：
2017-07
影响因子：
4.4
通讯作者：
Polf JC
中科院分区：
文献类型：
--
作者：
Draeger E;Peterson S;Mackin D;Chen H;Beddar S;Polf JC
一种用于医学应用的康普顿成像方法，包括新的能量确定和数据过滤技术，已经使用具有已知发射线的几个点源进行了测试。使用原型康普顿相机，最近距离方法技术已被用于确定入射γs的初始能量，并确保重建的源位置在距已知γ源位置的可接受距离内。进一步的分析是通过实施康普顿线过滤技术，只保留那些在第一次相互作用中的沉积能量与康普顿方程预测的理论能量沉积相匹配的相互作用。使用这种新的事件滤波方法，我们看到γ点源横向剖面的半峰全宽比标准康普顿成像方法提高了70%，并且重建图像的空间分辨率优于2 mm。此外，这种新的康普顿成像方法能够重建在用临床质子放射治疗束照射水箱期间发射的γ射线的扩展源。
A Compton imaging method for medical applications that includes new energy determination and data filtering techniques has been tested using several point sources with known emission lines. Using a prototype Compton camera, a distance-of-closest approach technique has been employed to determine the initial energy of the incoming γs and to ensure the reconstructed source position is within an acceptable distance from the known γ source location. Further analysis is done by implementing a Compton line filtering technique, keeping only those interactions whose deposited energy in the first interaction matches the theoretical energy deposition predicted by the Compton equation. Using this new event filtering method, we see improvements in the full width at half maximum in the lateral profiles of γ point sources of up to 70% over standard Compton imaging methods, as well as achievable spatial resolutions in the reconstructed images of better than 2 mm. In addition, this new Compton imaging method was able to reconstruct an extended source of γ rays emitted during irradiation of a water tank with a clinical proton radiotherapy beam.