Dual-Resonance (16/32 MHz) Piezoelectric Transducer With a Single Electrical Connection for Forward-Viewing Robotic Guidewire.
Dual-Resonance (16/32 MHz) Piezoelectric Transducer With a Single Electrical Connection for Forward-Viewing Robotic Guidewire.
复制标题
DOI：
10.1109/tuffc.2022.3150746
复制
发表时间：
2022-04
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
外周动脉疾病（PAD）影响着全球2亿多人。微创血管内手术可以提供救济和挽救肢体，同时减少受伤率和恢复时间。不幸的是，当遇到钙化的慢性完全闭塞时，约25%的血管内手术由于无法使用荧光透视提供的视图推进导丝而失败。为了使亚毫米，机器人可操纵的导丝穿过这些闭塞，一种新型的单元件，双波段换能器的开发，提供同时多频，前视成像，具有高穿透深度和高空间分辨率，而只需要一个单一的电连接。描述了该器械的设计、制造和声学表征，并在与自动操纵导丝集成后在离体猪动脉中证明了概念验证成像。所开发换能器的测量中心频率为16和32 MHz，− 6 dB部分带宽分别为73%和23%。当对深度为5 mm的0.2 mm金属丝目标进行成像时，在16 MHz和32 MHz下形成的图像中，测得的− 6 dB目标宽度分别为0.498 ± 0.02 mm和0.268 ± 0.01 mm。测量的SNR值分别为33.3 dB和21.3 dB。离体动脉的3D图像证明了在16 MHz下可视化血管形态的高穿透性和在32 MHz下分辨靠近换能器的小特征的能力。使用在两个频率下同时采集的图像作为基于导丝的集成前视成像系统的一部分，介入医生可以可视化推进导丝的最佳路径，以改善PAD患者的结局。
Peripheral artery disease (PAD) affects more than 200 million people globally. Minimally-invasive endovascular procedures can provide relief and salvage limbs while reducing injury rates and recovery times. Unfortunately, when a calcified chronic total occlusion is encountered, ~25% of endovascular procedures fail due to the inability to advance a guidewire using the view provided by fluoroscopy. To enable a sub-millimeter, robotically-steerable guidewire to cross these occlusions, a novel single-element, dual-band transducer is developed that provides simultaneous multi-frequency, forward-viewing imaging with high penetration depth and high spatial resolution while requiring only a single electrical connection. The design, fabrication, and acoustic characterization of this device are described, and proof-of-concept imaging is demonstrated in an ex vivo porcine artery after integration with a robotically-steered guidewire. Measured center frequencies of the developed transducer were 16 and 32 MHz, with −6 dB fractional bandwidths of 73% and 23%, respectively. When imaging a 0.2-mm wire target at a depth of 5 mm, measured −6 dB target widths were 0.498 ± 0.02 mm and 0.268 ± 0.01 mm for images formed at 16 MHz and 32 MHz, respectively. Measured SNR values were 33.3 dB and 21.3 dB, respectively. 3D images of the ex vivo artery demonstrate high penetration for visualizing vessel morphology at 16 MHz and ability to resolve small features close to the transducer at 32 MHz. Using images acquired simultaneously at both frequencies as part of an integrated forward-viewing, guidewire-based imaging system, an interventionalist could visualize the best path for advancing the guidewire to improve outcomes for patients with PAD.