How pain and analgesics disturb sleep
How pain and analgesics disturb sleep
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DOI：
10.1097/01.ajp.0000129757.31856.f7
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发表时间：
2005-09-01
影响因子：
2.9
通讯作者：
Dubray, C
中科院分区：
文献类型：
--
作者：
Onen, SH;Onen, F;Dubray, C
目的：临床经验和具体调查表明，疼痛与睡眠障碍密切相关。本综述的目的是首先描述与疼痛性疾病和镇痛药相关的睡眠障碍，其次提出这些睡眠障碍的管理可能性。方法：提出的观点主要是基于客观的休息活动和睡眠研究，使用活动记录和多导睡眠图。结果：多导睡眠图和活动记录研究描述了显着的睡眠障碍患者患有不同的疼痛障碍。这些干扰是：睡眠效率降低和睡眠结构改变，其特征在于觉醒增加和第1阶段非快速眼动睡眠，与减少的慢波睡眠和快速眼动睡眠相关。睡眠障碍可能与疼痛和镇痛或镇静药物administration.Conclusion：如果许多因素，包括疼痛，疾病过程本身，以及药物，可能会干扰睡眠，睡眠障碍也可能会对疼痛的疾病的自然过程产生不利影响。改善疼痛性疾病患者的睡眠数量和质量可以打破这种恶性循环，从而提高患者的整体健康和生活质量。
Objective: Clinical experiences as well as specific investigations show that pain and sleep disturbances are closely correlated. The aims of this review are first to describe sleep disturbances related to painful medical diseases and analgesics and secondly to propose management possibilities for these sleep disturbances.Method: The viewpoints presented were based mainly on objective rest activity and sleep studies using actigraphy and polysomnography.Results: Polysomnographic and actigraphic studies have described significant sleep disturbances in patients suffering from different pain disorders. These disturbances are: reduced sleep efficiency and altered sleep architecture characterized by increased wakefulness and stage 1 non-rapid eye movement sleep, associated with diminished slow wave sleep and rapid eye movement sleep. Sleep disturbances may be related to pain and to the analgesic or sedative medications administered.Conclusion: If many factors, including pain, disease process per se, as well as medication, could disturb sleep, sleep disturbances may also adversely affect the natural course of the painful disease. Improving sleep quantity and quality in patients with painful disorders may break this vicious circle and as consequence enhance the patients' overall health and quality of life.