Application of nanotechnology in biomedicine.
Application of nanotechnology in biomedicine.
复制标题
纳米技术在生物医学中的应用。
DOI：
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发表时间：
2007
影响因子：
0.6
通讯作者：
T. Nandedkar
中科院分区：
文献类型：
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作者：
Rajshri M Navalakhe;T. Nandedkar
纳米技术是在纳米范围内原子、分子和大分子水平上发展的工程器件。纳米粒子在医学诊断和治疗等领域具有潜在的应用前景。目前正在开发用于诊断癌症和传染病的纳米技术设备，这些设备可以帮助早期发现疾病。纳米技术的进步在药物发现、药物传递和基因/蛋白质传递等治疗领域也被证明是有益的。纳米颗粒可以通过不同的方法构建，从而可以在所需的位置上发挥作用。本文综述了纳米颗粒作为诊断和治疗药物在医学上的一些应用，这些应用在临床水平上是安全的。另一方面，随着颗粒变得越来越小，它们对肺部造成伤害的可能性也在增加。因此，有必要对纳米颗粒的安全性进行研究。
Nanotechnology is the development of engineered devices at the atomic, molecular and macromolecular level in nanometer range. Nanoparticles have potential application in medical field including diagnostics and therapeutics. Nanotechnology devices are being developed for diagnosis of cancer and infectious diseases which can help in early detection of the disease. Advances in nanotechnology also proved beneficial in therapeutic field such as drug discovery, drug delivery and gene/protein delivery. Nanoparticles can be constructed by various methodology so that effect can be targeted at desired site. In this review, some of the applications of nanoparticles in medicine as diagnostics and therapeutics which can be employed safely at the clinical level have been described. On other hand, as the particles become generally smaller their likehood of causing harm to the lung increases. Therefore, there is a need to study safety of nanoparticles.