DIAGNOSTIC SIGNIFICANCE OF THYROID MICROSOMAL ANTIBODIES IN RANDOMLY SELECTED POPULATION
DIAGNOSTIC SIGNIFICANCE OF THYROID MICROSOMAL ANTIBODIES IN RANDOMLY SELECTED POPULATION
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随机选择人群中甲状腺微粒体抗体的诊断意义
DOI：
10.1016/s0140-6736(80)92276-x
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
T. Welborn
中科院分区：
文献类型：
--
作者：
B. R. Hawkins;B. R. Hawkins;B. R. Hawkins;R. Dawkins;R. Dawkins;R. Dawkins;H. Burger;H. Burger;H. Burger;I. Mackay;I. Mackay;I. Mackay;P. S. Cheah;P. Cheah;P. S. Cheah;S. Whittingham;S. Whittingham;S. Whittingham;Y. Patel;Y. Patel;Y. Patel;T. Welborn;T. Welborn;T. Welborn
在西澳大利亚州布塞尔顿人群中进行的一项纵向研究发现，个体存在持续性和短暂性甲状腺微粒体抗体（TMA）。82例持续性TMA患者中有59例（72%），25例近期发生TMA患者中有18例（72%），53例一过性抗体患者中有12例（23%）被发现患有亚临床甲状腺功能减退症，如高血清促甲状腺激素浓度所示。本研究揭示了持续性或近期获得性TMA的高特异性、敏感性和预测价值。
A longitudinal study among the population of Busselton, Western Australia, has identified individuals with persistent and transient thyroid microsomal antibodies (TMA). 59 (72%) of 82 subjects with persistent TMA, 18 (72%) of 25 with recently developed TMA, and 12(23%) of 53 with transient antibody were found to have subclinical hypothyroidism, as indicated by high serum thyroid stimulating hormone concentrations. This study reveals the high specificity, sensitivity, and predictive value of persistent or recently acquired TMA.