Clinical Characteristics of Pregnancy-Associated Central Serous Chorioretinopathy in the Chinese Population.
Clinical Characteristics of Pregnancy-Associated Central Serous Chorioretinopathy in the Chinese Population.
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中国人群妊娠相关中心性浆液性脉络膜视网膜病变的临床特征
DOI：
10.1155/2021/5580075
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发表时间：
2021
影响因子：
1.9
通讯作者：
Xu G
中科院分区：
文献类型：
--
作者：
Yu J;Li L;Jiang C;Chang Q;Xu G
探讨中国人群妊娠相关性中心性浆液性脉络膜视网膜病变（CSC）的临床特点。 回顾性分析了2012年2月至2019年10月诊断为妊娠相关CSC的患者的病历。收集最佳矫正视力（BCVA）、症状持续时间、妊娠相关医疗信息和光学相干断层扫描（OCT）图像。 纳入9例患者（11只眼）。五名妇女是在他们的第一次怀孕，四个是在他们的第二次怀孕，其中两个经历了CSC在他们的第一次怀孕以及。平均年龄为35.00 ± 3.97岁。首次访视时的平均症状持续时间为19.73 ± 13.65天。CSC发生时的平均胎龄为27.11 ± 2.09周。初次访视时的平均BCVA（最小分辨角的对数（logMAR））为0.36 ± 0.18（Snellen 20/45，范围20/100-20/25）。所有患眼在首次访视时OCT图像上均显示视网膜下高反射纤维蛋白。4例患者（4只眼）在液体消退前失访。末次访视时的平均BCVA为logMAR 0.10 ± 0.15（Snellen 20/25，范围20/50-20/20））。年龄最大的患者的一只眼睛在产后26个月时出现持续性视网膜下积液。半剂量光动力疗法（PDT）后，视网膜下液完全消退;然而，半剂量PDT后30个月，中心凹的椭圆体区仍然不连续。其余6只眼均在分娩前后视网膜下积液自行消退，恢复完整的椭圆体区。 中国人妊娠相关性CSC大多发生在妊娠晚期，通常在分娩前后自发恢复，最终视力良好。然而，患者可能需要长期随访，直到视网膜下液完全消退并检测复发。如果分娩后视网膜下液量几乎没有减少，可以早期给予半剂量PDT。
To investigate the clinical characteristics of pregnancy-associated central serous chorioretinopathy (CSC) in the Chinese population. The medical records of patients diagnosed with pregnancy-associated CSC from February 2012 to October 2019 were retrospectively reviewed. Best-corrected visual acuity (BCVA), symptom duration, pregnancy-related medical information, and optical coherence tomography (OCT) images were collected. Nine patients (11 eyes) were included. Five women were in their first pregnancy and four were in their second pregnancy, two of whom experienced CSC in their first pregnancy as well. The mean age was 35.00 ± 3.97 years. The mean symptom duration at the initial visit was 19.73 ± 13.65 days. The mean gestational age at the time of development of CSC was 27.11 ± 2.09 weeks. The mean BCVA (logarithm of the minimum angle of resolution (logMAR)) at the initial visit was 0.36 ± 0.18 (Snellen 20/45, range 20/100–20/25). All eyes showed subretinal hyperreflective fibrin on OCT images at the initial visit. Four patients (4 eyes) were lost to follow-up before fluid resolution. The mean BCVA at the final visit was logMAR 0.10 ± 0.15 (Snellen 20/25, range 20/50–20/20)). One eye in the oldest patient had persistent subretinal fluid at 26 months postpartum. The subretinal fluid resolved completely after half-dose photodynamic therapy (PDT); however, the ellipsoid zone at the fovea remained discontinuous at 30 months after half-dose PDT. The remaining six eyes all showed spontaneous resolution of subretinal fluid around delivery and regained intact ellipsoid zone. Pregnancy-associated CSC in Chinese developed mostly in the third trimester and usually recovered spontaneously around delivery with good final visual acuity. However, patients might require long-term follow-up until complete resolution of subretinal fluid and to detect recurrences. Half-dose PDT can be administered early if there is little reduction in the amount of subretinal fluid after delivery.
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影响因子：
7.8
作者：
Chen M;Rajapakse D;Fraczek M;Luo C;Forrester JV;Xu H
通讯作者：
Xu H
影响因子：
0.3
作者：
Chakraborti, Chandana;Samanta, Swapan Kumar;Mondal, Ramkrishna
通讯作者：
Mondal, Ramkrishna
影响因子：
0.9
作者：
Hirji, Nashila;Watt, Lynda;Richardson, Emma
通讯作者：
Richardson, Emma
DOI：
10.1097/iae.0000000000001443
发表时间：
2017-10
期刊：
Retina (Philadelphia, Pa.)
影响因子：
--
作者：
Daruich A;Matet A;Marchionno L;De Azevedo JD;Ambresin A;Mantel I;Behar-Cohen F
通讯作者：
Behar-Cohen F
影响因子：
2
作者：
Maggio E;Polito A;Freno MC;Pertile G
通讯作者：
Pertile G