Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
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DOI：
10.2147/opth.s99394
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发表时间：
2016-01-01
影响因子：
2.2
通讯作者：
Uusitalo, Hannu
中科院分区：
文献类型：
--
作者：
Huhtala, Anne;Pietila, Juhani;Uusitalo, Hannu
目的：本研究的目的是回顾和荟萃分析报告的飞秒（FS）激光用于激光辅助原位角膜磨镶术（LASIK）的疗效、可预测性和安全性（作为主要结局）以及角膜瓣厚度测量和术前和术后并发症（作为次要结局）是否存在差异。方法：对PubMed、Science Direct、Scopus和科克伦中心试验图书馆数据库进行了全面的文献检索，以识别FS激光用于LASIK的相关前瞻性随机对照试验。结果：根据疗效，IntraLase FS 10和30 kHz的结果最好。基于可预测性和安全性，各种FS激光之间没有差异。FEMTO LDV和IntraLase FS 60 kHz产生了最准确的皮瓣厚度。IntraLase和Wavelight SF 200的术中并发症最少。IntraLase、Visumax和Wavelight FS 200术后并发症最少。结论：不同FS激光的疗效和术中术后并发症存在差异。所有FS激光在LASIK中制作角膜瓣是可预测的和安全的。
Purpose: The aim of this study was to review and meta-analyze whether there are differences between reported femtosecond (FS) lasers for laser-assisted in situ keratomileusis (LASIK) in terms of efficacy, predictability, and safety as primary outcomes and corneal flap thickness measurements and pre-and postoperative complications as secondary outcomes.Methods: A comprehensive literature search of PubMed, Science Direct, Scopus, and Cochrane CENTRAL Trials Library databases was conducted to identify the relevant prospective randomized controlled trials of FS lasers for LASIK. Thirty-one articles describing a total of 5,404 eyes were included.Results: Based on efficacy, IntraLase FS 10 and 30 kHz gave the best results. Based on predictability and safety, there were no differences between various FS lasers. FEMTO LDV and IntraLase FS 60 kHz produced the most accurate flap thicknesses. IntraLase and Wavelight SF200 had the fewest intraoperative complications. IntraLase, Visumax, and Wavelight FS200 had the most seldom postoperative complications.Conclusion: There were dissimilarities between different FS lasers based on efficacy and intraoperative and postoperative complications. All FS lasers were predictable and safe for making corneal flaps in LASIK.