Lipoprotein lipase activity of human adipose tissue in health and in some diseases with hyperlipidemia as a common feature.
Lipoprotein lipase activity of human adipose tissue in health and in some diseases with hyperlipidemia as a common feature.
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健康人和某些以高脂血症为共同特征的疾病中人体脂肪组织的脂蛋白脂肪酶活性。
DOI：
10.1111/j.0954-6820.1973.tb10608.x
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发表时间：
2009
影响因子：
--
通讯作者：
B. Persson
中科院分区：
文献类型：
--
作者：
B. Persson
测定了50例健康男性和50例健康女性脂肪组织脂蛋白脂酶活性（LPLA）、血清甘油三酯、胆固醇、游离脂肪酸（FFA）、血糖和乙酰乙酸。以同样的方式研究了动脉粥样硬化疾病、糖尿病和糖耐量受损、高酒精消耗、尿毒症和一些粘液水肿、肾病和胰岛瘤患者的受试者组。与大多数正常和高脂血症受试者相比，LPLA和血脂之间的关系似乎没有被动脉粥样硬化疾病或不同程度的葡萄糖耐受不良所改变。相反，在饮酒过量的受试者中，LPLA正常或偏高，尽管高脂血症的发病率很高。30例尿毒症受试者的特征是低LPLA，血清甘油三酯、胆固醇和血乙酰乙酸水平升高，而血清FFA低。
Adipose tissue lipoprotein lipase activity (LPLA), serum triglycerides, cholesterol and free fatty acids (FFA), blood glucose and aceto-acetate have been determined in groups of 50 healthy men and 50 healthy women. Groups of subjects with atherosclerotic disease, diabetes and impaired glucose tolerance, high alcohol consumption, uremia and some patients with myxedema, nephrosis and insuloma have been studied in the same way. In comparison with a majority of normo- and hyperlipidemic subjects the relation between LPLA and serum lipids did not seem to be modified by either atherosclerotic disease or different degrees of glucose intolerance. On the contrary, in subjects with alcohol overconsumption LPLA was normal or high, in spite of a high incidence of hyperlipidemia. Thirty uremic subjects were characterized by low LPLA, increased levels of serum triglycerides, cholesterol and blood aceto-acetate, while serum FFA was low.