Complete genome sequences and phylogenetic analysis of West Nile virus strains isolated from the United States, Europe, and the Middle East
Complete genome sequences and phylogenetic analysis of West Nile virus strains isolated from the United States, Europe, and the Middle East
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DOI：
10.1006/viro.2002.1449
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发表时间：
2002-06-20
期刊：
影响因子：
3.7
通讯作者：
Roehrig, JT
中科院分区：
文献类型：
--
作者：
Lanciotti, RS;Ebel, GD;Roehrig, JT
八种西尼罗河（WN）病毒株（埃及 1951、罗马尼亚 1996-MQ、意大利 1998-马、纽约 1999-马、MD 2000-crow265、NJ 2000MQ5488、NY 2000-grouse3282 和 NY 2000-crow3356）的完整核苷酸序列确定。系统发育树是根据这八种病毒的比对核苷酸序列以及所有其他先前发布的完整 WIN 病毒基因组序列构建的。系统发育树揭示了 WIN 病毒的两个遗传谱系的存在，谱系 1 WIN 病毒已从美国东北部、欧洲、以色列、非洲、印度、俄罗斯和澳大利亚分离出来。仅在撒哈拉以南非洲和马达加斯加分离到 Lineage 2 WIN 病毒。谱系1病毒可进一步细分为三个单系进化枝。 (C) 2002 年爱思唯尔科学（美国）。
The complete nucleotide sequences of eight West Nile (WN) virus strains (Egypt 1951, Romania 1996-MQ, Italy 1998-equine, New York 1999-equine, MD 2000-crow265, NJ 2000MQ5488, NY 2000-grouse3282, and NY 2000-crow3356) were determined. Phylogenetic trees were constructed from the aligned nucleotide sequences of these eight viruses along with all other previously published complete WIN virus genome sequences. The phylogenetic trees revealed the presence of two genetic lineages of WIN viruses, Lineage 1 WIN viruses have been isolated from the northeastern United States, Europe, Israel, Africa, India, Russia, and Australia. Lineage 2 WIN viruses have been isolated only in sub-Saharan Africa and Madagascar. Lineage 1 viruses can be further subdivided into three monophyletic clades. (C) 2002 Elsevier Science (USA).