CONTROL OF VENTILATION DURING SPEECH
CONTROL OF VENTILATION DURING SPEECH
复制标题
DOI：
10.1152/jappl.1971.31.6.870
复制
发表时间：
1971-01-01
影响因子：
3.3
通讯作者：
MEAD, J
中科院分区：
文献类型：
--
作者：
BUNN, JC;MEAD, J
方法受试者坐在一个空气冷却的体积描记器中，颈部有一个气密密封件将身体和头部分隔开（2）。用连接到体腔的肺活量计测量肺活量。待呼吸的气体被传递到头部腔室的后部，抵靠挡板，并通过受试者嘴正前方的1 -5英寸的孔离开腔室。流速足以防止呼出空气的再呼吸。将采样管用胶带粘在面部，并将其开口尖端定位在一个鼻孔的开口内。潮气末Pcoz从这个网站上取样，并与快速响应红外分析仪测量。在大多数受试者中，在讲话期间有足够的鼻流量，因此在每个时期的几个点可以获得可接受的二氧化碳平台。CO2和容量信号以1 mm/组或0.5 mm/组的纸速以电子照相的方式记录。通气记录为1分钟间隔内所有吸气波动的总和。相应的肺泡通气量是根据假设的死腔体积（单位：毫升）等于体重（单位：磅）来估计的（7）。在一组测量中，受试者呼吸空气。在第二组中，他们呼吸了添加了二氧化碳的空气。3-3.5%的CO2混合物导致大约加倍的自主通气。
METHODSSubjects sat in an air-cooled plethysmograph with an airtight seal at the neck separating the body and head charnbers (2). V 1 o umes were measured with a spirometer attached to the body chamber. The gas to be breathed was passed into the back of the head chamber, against a baffle,-and left the chamber through a l-5-inch hole directly in front of the subject’s mouth. The flow rate was sufficient to preyen t rebreathing of expired air. A sampling tube was taped to the face and positioned with its open tip just within the opening of one nostril. End-tidal Pcoz was sampled from this site and measured with a rapidly responding infrared analyzer. In most subjects there was sufficient nasal flow during speech so that acceptable plateaus of carbon dioxide could be obtained at several points during each period.CO2 and volume signals were recorded oscillographically at a paper speed of either 1 mm/set or 0.5 mm/set. Ventilation was recorded as the sum of all inspiratory excursions during 1-min intervals. Corresponding alveolar ventilation was estimated based on an assumed dead space volume in milliliters equal to the body weight in pounds (7). In one set of measurements, subjects breathed air. In the second set, they breathed air with CO2 added. The mixtures of 3-3.5% of CO2 resulted in approximately a doubling of spontaneous ventilation.