Fatal and non-fatal cases of lime sulfide exposure and pathogenetic mechanisms underlying pancreatic injury : Case reports with an animal experiment

Fatal and non-fatal cases of lime sulfide exposure and pathogenetic mechanisms underlying pancreatic injury : Case reports with an animal experiment
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硫化石灰暴露的致命和非致命病例以及胰腺损伤的发病机制:动物实验病例报告

DOI:
10.1016/j.jflm.2012.02.027
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发表时间:
2012
期刊:
影响因子:
1.5
通讯作者:
Ohshima T
Ohshima T
中科院分区:
医学4区
文献类型:
--
作者:
Zuka M;Chinaka S;Matsumoto Y;Takayama N;Hitomi Y;Nakamura H;Ohshima T

文献摘要

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在法医学实践中,很少遇到经口途径的硫化石灰中毒,而硫化氢中毒却很常见。我们在这里报告了两起致命的硫化石灰中毒病例以及几起相关病例,此外在相似浓度下在动物模型中诱发了组织学损伤和急性炎症。我们还评估了硫化物和硫代硫酸盐的浓度,并推测了这些病例中胰腺损伤的原因。
Lime sulfide poisoning by the oral route is rarely encountered in the practice of forensic science, whereas hydrogen sulfide poisoning is seen frequently. We report here two cases of fatal lime sulfide poisoning with several related cases and in addition induced histological damage with acute inflammation in animal models under at similar concentrations. We also evaluated sulfide and thiosulfate concentrations and speculated as to the cause of pancreatic damage in these cases.