Construction of an unstable Ring-X chromosome bearing the autosomal dopa decarboxylase gene in Drosophila melanogaster and analysis of Ddc mosaics.
Construction of an unstable Ring-X chromosome bearing the autosomal dopa decarboxylase gene in Drosophila melanogaster and analysis of Ddc mosaics.
复制标题
果蝇中携带常染色体多巴脱羧酶基因的不稳定 Ring-X 染色体的构建和 Ddc 嵌合体的分析。
DOI：
10.1093/genetics/115.2.305
复制
发表时间：
1987
期刊：
影响因子：
3.3
通讯作者：
White,K
中科院分区：
文献类型：
--
作者：
Gailey,DA;Bordne,DL;Vallés,AM;Hall,JC;White,K
An unstable Ring-Xchromosome,Ddc+-Ring-Xcarrying a cloned Dopa decarboxylase (Ddc) encoding segment was constructed. The construction involved a double recombination event between the unstableRing-X, R(1)wvCand aRod-Xchromosome which contained aP-element mediatedDdc+insert. The resultingDdc+-Ring-Xchromosome behaves similarly to the parent chromosome with respect to somatic instability. TheDdc+-Ring-Xchromosome was used to generateDdcmosaics. Analyses ofDdcmosaics revealed that while there was no absolute requirement for theDdc+expression in either the epidermis or the nervous system, very large mutant clones did affect the viability of the mosaic.
