Burden of Crohn's Disease in the United States Medicaid Population, 2010-2019.
Burden of Crohn's Disease in the United States Medicaid Population, 2010-2019.
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2010-2019 年美国医疗补助人群的克罗恩病负担。
DOI：
10.1016/j.cgh.2023.05.002
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Brant,StevenR
中科院分区：
文献类型：
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作者：
Hutfless,Susan;Jasper,RyanA;Chen,Po-Hung;Joseph,Shelly;Miller,Steve;Brant,StevenR
背景与目标25%的美国人口参加了医疗补助计划。自2014年平价医疗法案扩大以来，克罗恩病（CD）的发病率尚未在医疗补助人群中估计。我们的目的是估计CD的发病率和患病率的年龄，性别，和race.MethodsWe确定了所有2010-2019年医疗补助CD遭遇使用的国际疾病分类，临床修改版本9和10的代码。纳入了≥2次CD发作的个体。对其他定义（例如，≥1次CD发作）进行敏感性分析。发生率要求在首次CD就诊日期之前有≥1年的医疗补助资格（2013-2019）。我们以整个医疗补助人群作为分母计算CD患病率和发病率。发生率按日历年、年龄、性别和种族分层。Poisson回归模型检查CD相关的人口统计学特征。我们比较了人口统计学和治疗的整个医疗补助人口与多个CD病例定义使用百分比和medium.ResultsA共197,553受益人有≥2 CD遭遇。每10万人CD点患病率从56（2010年）上升到88（2011年）再上升到165（2019年）。CD发病率/10万人-年为18（2013年）和13（2019年）。较高的发病率和患病率与女性、白色或多种族受益人相关。随后几年，患病率上升。发病率随着时间的推移而下降。ConclusionsFrom 2010 to 2019，Medicaid population CD prevalence increased while incidence decreased from 2013 to 2019.总体医疗补助CD发病率和患病率范围与之前的大型管理数据库研究一致。
Background & AimsTwenty-five percent of the United States population is enrolled in Medicaid. Rates of Crohn’s disease (CD) have not been estimated in the Medicaid population since the Affordable Care Act expansion in 2014. We aimed to estimate the incidence and prevalence of CD by age, sex, and race.MethodsWe identified all 2010-2019 Medicaid CD encounters using codes from the International Classification of Diseases, Clinical Modification versions 9 and 10. Individuals with ≥2 CD encounters were included. Sensitivity analyses were performed on other definitions (eg, ≥1 CD encounter). Incidence required ≥1 year of Medicaid eligibility prior to first CD encounter date (2013-2019). We calculated CD prevalence and incidence using the entire Medicaid population as the denominator. Rates were stratified by calendar year, age, sex, and race. Poisson regression models examined CD-associated demographic characteristics. We compared demographics and treatments of the entire Medicaid population with the multiple CD case definitions using percent and median.ResultsA total of 197,553 beneficiaries had ≥2 CD encounters. The CD point prevalence per 100,000 persons rose from 56 (2010) to 88 (2011) to 165 (2019). CD incidence per 100,000 person-years was 18 (2013) and 13 (2019). Higher incidence and prevalence rates correlated with female, white, or multiracial beneficiaries. Prevalence rates rose in later years. Incidence decreased over time.ConclusionsFrom 2010 to 2019, Medicaid population CD prevalence increased while incidence decreased from 2013 to 2019. Overall Medicaid CD incidence and prevalence ranges align with prior large administrative database studies.