Conditions, pathogenesis, and progression of diabetic kidney disease and early decliner in Japan
Conditions, pathogenesis, and progression of diabetic kidney disease and early decliner in Japan
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DOI：
10.1136/bmjdrc-2019-000902
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发表时间：
2020-01-01
影响因子：
4.1
通讯作者：
Matsuyama, Yutaka
中科院分区：
文献类型：
--
作者：
Yoshida, Yui;Kashiwabara, Kosuke;Matsuyama, Yutaka
Objective Glomerular filtration rate (GFR) decreases without or prior to the development of albuminuria in many patients with diabetes. Therefore, albuminuria and/or a low GFR in patients with diabetes is referred to as diabetic kidney disease (DKD). A certain proportion of patients with diabetes show a rapid progressive decline in renal function in a unidirectional manner and are termed early decliners. This study aimed to elucidate the prevalence of DKD and early decliners and clarify their risk factors.Research design and methods This combination cross-sectional and cohort study included 2385 patients with diabetes from 15 hospitals. We defined DKD as a urinary albumin to creatinine ratio (ACR) >= 30 mg/gCr and/or estimated glomerular filtration rate (eGFR)
