Binding between DNA and Carbon Nanotubes Strongly Depends upon Sequence and Chirality
Binding between DNA and Carbon Nanotubes Strongly Depends upon Sequence and Chirality
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DOI：
10.1021/la500013c
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发表时间：
2014-03-25
期刊：
影响因子：
3.9
通讯作者：
Jagota, Anand
中科院分区：
文献类型：
--
作者：
Shankar, Akshaya;Mittal, Jeetain;Jagota, Anand
某些单链DNA(SsDNA)序列识别它们的伙伴单壁碳纳米管(CNT)。在这里，我们报告了表面活性剂分子从几个碳纳米管物种中去除几个单链DNA序列的活化能。我们发现，DNA序列在其CNT识别伙伴上系统性地比在非伙伴物种上具有更高的激活能。例如，DNA序列(TAT)(4)在(9，1)CNT上的激活能远低于其伴侣(6，5)CNT，而DNA序列(CCA)(10)与其伴侣(9，1)CNT的结合比(6，5)CNT强。(6，5)和(9，1)碳纳米管具有相同的直径但不同的电子性质，表明激活能差异与电子性质有关。测定了从11-聚(TAT)(3)TA到21-聚(TAT)(7)三种不同碳纳米管物种(9，1)、(6，5)和(8，3)上紧密相关序列的长度增长激活能。对于较短的序列，碳纳米管上的激活能随序列周期性地变化。
Certain single-stranded DNA (ssDNA) sequences are known to recognize their partner single-walled carbon nanotube (CNT). Here, we report on activation energies for the removal of several ssDNA sequences from a few CNT species by a surfactant molecule. We find that DNA sequences systematically have higher activation energy on their CNT recognition partner than on non-partner species. For example, the DNA sequence (TAT)(4) has much lower activation energy on the (9,1) CNT than on its partner (6,5) CNT, whereas the DNA sequence (CCA)(10) binds strongly to its partner (9,1) CNT compared to (6,5) CNT. The (6,5) and (9,1) CNTs have the same diameter but different electronic properties, suggesting that the activation energy difference is related to electronic properties. The activation energies of increasing lengths of closely related sequences from the 11-mer (TAT)(3)TA to the 21-mer (TAT)(7) on three different CNT species (9,1), (6,5), and (8,3) were measured. For the shorter sequences, the activation energy on the CNT varies periodically with the sequence.