The effect of spectral filters on VEP and alpha-wave responses.
The effect of spectral filters on VEP and alpha-wave responses.
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DOI：
10.1016/j.optom.2015.07.003
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发表时间：
2016-04
影响因子：
2.3
通讯作者：
Ciuffreda KJ
中科院分区：
文献类型：
--
作者：
Willeford KT;Fimreite V;Ciuffreda KJ
光谱滤波器用于治疗创伤性脑损伤（TBI）患者的光敏感性;然而，这些滤波器对正常视觉功能的影响尚未阐明。因此，本研究旨在确定光谱滤波器对视觉正常人群中客观测量的视觉诱发电位（VEP）和α波反应的影响。对20名视力正常者进行了全视野（15 ° H × 17 ° V）图形反转VEP（20 ′方格大小，平均亮度52 cd/m2）检查。它们用四个直观色度计衍生的宽带光谱滤光片（即，灰色/中性密度、蓝色、黄色和红色），其对于测试刺激产生类似的亮度值。记录VEP N75、P100潜伏期及VEP振幅。功率谱分析用于推导α波段所选9 - 11 Hz分量在每个频率和峰值频率下的相应功率。与基线相比，N75和P100潜伏期均随着每种滤器的添加而增加。此外，每个滤波器在数值上降低了会话内幅度相对于基线的变化。对平均VEP振幅或α波参数均无显著影响。直观色度计过滤器显著增加了N75和P100的亮度，这种效果主要归因于亮度（约75%），并且在某些情况下，特定的光谱效果（例如，蓝色和红色）。VEP振幅和α功率未受到显著影响。这些研究结果提供了一个重要的参考，无论是振幅或功率变化的光敏感，年轻的临床群体可以进行比较。
Spectral filters are used to treat light sensitivity in individuals with traumatic brain injury (TBI); however, the effect of these filters on normal visual function has not been elucidated. Thus, the current study aimed to determine the effect of spectral filters on objectively-measured visual-evoked potential (VEP) and alpha-wave responses in the visually-normal population. The full-field (15°H × 17°V), pattern-reversal VEP (20′ check size, mean luminance 52 cd/m2) was administered to 20 visually-normal individuals. They were tested with four Intuitive-Colorimeter-derived, broad-band, spectral filters (i.e., gray/neutral density, blue, yellow, and red), which produced similar luminance values for the test stimulus. The VEP N75 and P100 latencies, and VEP amplitude, were recorded. Power spectrum analysis was used to derive the respective powers at each frequency, and peak frequency, for the selected 9–11 Hz components of the alpha band. Both N75 and P100 latencies increased with the addition of each filter when compared to baseline. Additionally, each filter numerically reduced intra-session amplitude variability relative to baseline. There were no significant effects on either the mean VEP amplitude or alpha wave parameters. The Intuitive Colorimeter filters significantly increased both N75 and P100 latencies, an effect which is primarily attributable (∼75%) to luminance, and in some cases, specific spectral effects (e.g., blue and red). VEP amplitude and alpha power were not significantly affected. These findings provide an important reference to which either amplitude or power changes in light-sensitive, younger clinical groups can be compared.