Synthetic insulin-like growth factor II.
Synthetic insulin-like growth factor II.
复制标题
合成胰岛素样生长因子 II。
DOI：
10.1016/s0006-291x(85)80177-7
复制
发表时间：
1985
影响因子：
3.1
通讯作者：
Westphal,M
中科院分区：
文献类型：
--
作者：
Li,CH;Yamashiro,D;HammondsJr,RG;Westphal,M
用固相法合成了含67个氨基酸残基和3个二硫键的人胰岛素样生长因子Ⅱ。通过色谱聚焦、高效液相色谱和氨基酸分析确定合成产物的均一性。在放射免疫分析和放射受体分析中，合成产物与天然激素是无法区分的。
Human insulin-like growth factor II with 67 amino acid residues and three disulfide bridges has been synthesized by the solid-phase method. Homogeneity of the synthetic product is ascertained by chromatofocusing, high performance liquid chromatography and amino acid analysis. In both radioimmunoassay and radioreceptor assay, the synthetic product is indistinquishable from the natural hormone.