Conserved hydrogen bonding in tetrahydrocarbazolone derivatives: influence of solution-state assembly on crystal form nucleation.
Conserved hydrogen bonding in tetrahydrocarbazolone derivatives: influence of solution-state assembly on crystal form nucleation.
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DOI：
10.1039/c4cc10453f
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发表时间：
2015-03
影响因子：
4.9
通讯作者：
Robert M. Edkins;Elliott Hayden;J. Steed;K. Fucke
中科院分区：
文献类型：
--
作者：
Robert M. Edkins;Elliott Hayden;J. Steed;K. Fucke
发现两种四氢咔唑酮衍生物具有多种非溶剂化结晶形式。FTIR光谱在溶液中检测到一个持续的二聚体基元，它保持在动力学晶体形式中。合理地引入立体体可以形成更稳定的单晶体。
Two tetrahydocarbazolone derivatives were found to show multiple unsolvated crystal forms. A persistent dimer motif was detected in solution by FTIR spectroscopy that is maintained in the kinetic crystal forms. Rationally introduced steric bulk induces the formation of a more stable catemeric form.