Coping and quality of life in patients awaiting lung transplantation.
Coping and quality of life in patients awaiting lung transplantation.
复制标题
等待肺移植患者的应对和生活质量。
DOI：
10.1016/j.jpsychores.2008.04.009
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发表时间：
2008
影响因子：
4.7
通讯作者：
Blumenthal,JamesA
中科院分区：
文献类型：
--
作者：
Taylor,JessicaL;Smith,PatrickJ;Babyak,MichaelA;Barbour,KristaA;Hoffman,BensonM;Sebring,DeborahL;Davis,RDuane;Palmer,ScottM;Keefe,FrancisJ;Carney,RobertM;Csik,Iris;Freedland,KennethE;Blumenthal,JamesA
目的终末期肺部疾病(ESLD)患者的生活质量(QOL)显著降低。尽管应对策略与ESLD患者的生活质量相关，但特定的原发肺部疾病在多大程度上缓和了这种关系尚不清楚。方法我们调查了187名等待肺移植的患者，其中包括139名慢性阻塞性肺疾病(COPD)患者和48名囊性纤维化(CF)患者，探讨了应对、原发肺部疾病和生活质量之间的关系。参与者完成了心理生活质量、身体生活质量和应对策略的社会心理评估。结果对于COPD和CF患者，较高的积极应对水平(P<；.0001)和较低的脱离水平(P<；.0001)与较好的心理生活质量相关。对于躯体生活质量，我们观察到了原发病与应对的交互作用(P=0.01)，在COPD患者中，积极应对与较好的躯体生活质量相关，而在慢性阻塞性肺疾病患者中则不相关。结论应对与生活质量的关系可能随着原发肺部疾病的不同而不同。为了开发有效的干预措施来帮助患者成功地应对ESLD，可能需要考虑患者的原发病。
OBJECTIVEPatients with end-stage lung disease (ESLD) experience significant decrements in quality of life (QOL). Although coping strategies are related to QOL in patients with ESLD, the extent to which specific native lung disease moderates this relationship is unknown.METHODSWe investigated the relationship between coping, native lung disease, and QOL among 187 patients awaiting lung transplantation, including 139 patients with chronic obstructive pulmonary disease (COPD) and 48 with cystic fibrosis (CF). Participants completed a psychosocial battery assessing psychological QOL, physical QOL, and coping strategies.RESULTSFor both COPD and CF patients, higher levels of Active Coping (P<.0001) and lower levels of Disengagement (P<.0001) were associated with better psychological QOL. For physical QOL, we observed a Native Disease×Coping interaction (P=.01) such that Active Coping was associated with better physical QOL in patients with COPD but not in patients with CF.CONCLUSIONSThe relationship between coping and QOL may vary as a function of native lung disease. Patients' native disease may need to be considered in order to develop effective interventions to help patients cope successfully with ESLD.