Social and spatial changes induce multiple survival regimes for new neurons in two regions of the adult brain: An anatomical representation of time?
Social and spatial changes induce multiple survival regimes for new neurons in two regions of the adult brain: An anatomical representation of time?
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DOI：
10.1016/j.bbr.2005.08.018
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发表时间：
2006-02-15
影响因子：
2.7
通讯作者：
Nottebohm, F
中科院分区：
文献类型：
--
作者：
Barnea, A;Mishal, A;Nottebohm, F
雄性斑胸草雀饲养在家庭组最初被安置在小室内笼子里与其他三个同伴。在4-5个月大时，这些鸟用[H-3]-胸苷处理，然后单独或与其他斑胸草雀一起放置在大型户外鸟舍中。在更换饲养环境后40、60和150天进行新神经元计数。新的神经元在nidopallium caudale（NC）的招聘高于海马复合体（HC），但在这两个大脑区域，它是更高的共同圈养的鸟类比单独圈养的鸟类，这表明社会环境的复杂性影响新的神经元的生存。此外，新生神经元在头侧NC比在尾侧NC存活更长，神经元更新比HC更快和更显著。尽管这是间接的，但这可能是第一个表明大脑的不同部分在不同的时间间隔升级记忆，从而产生时间的解剖学表示。(c)2005 Elsevier B. V.保留所有权利。
Male zebra finches reared in family groups were housed initially in small indoors cages with three other companions. At 4-5 months of age these birds were treated with [H-3]-thymidine and then placed in large outdoors aviaries by themselves or with other zebra finches. Counts of new neurons were made 40,60 and 150 days after the change in housing. Recruitment of new neurons in nidopallium caudale (NC) was higher than in the hippocampal complex (HC); but in both brain regions it was higher in communally housed birds than in birds housed singly, Suggesting that the complexity of the social setting affects new neuron survival. In addition, the new neurons lived longer in rostral NC than ill its caudal Counterpart, and neuronal turnover was faster and more significant in NC than in HC. Albeit indirect, this may be the first suggestion that different parts of the brain upgrade memories at different time intervals, yielding an anatomical representation of time. (c) 2005 Elsevier B.V. All rights reserved.