A Prospective Cohort Study of Muscular and Performance Fitness and Incident Glaucoma: The Niigata Wellness Study
A Prospective Cohort Study of Muscular and Performance Fitness and Incident Glaucoma: The Niigata Wellness Study
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肌肉和表现健身与青光眼事件的前瞻性队列研究：新泻健康研究
DOI：
10.1123/jpah.2019-0660
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发表时间：
2020
影响因子：
3.1
通讯作者：
Sone Hirohito
中科院分区：
文献类型：
--
作者：
Kawakami Ryoko;Gando Yuko;Kato Kiminori;Sawada Susumu S.;Momma Haruki;Miyachi Motohiko;Lee I-Min;Blair Steven N.;Tashiro Minoru;Horikawa Chika;Matsubayashi Yasuhiro;Yamada Takaho;Fujihara Kazuya;Sone Hirohito
背景：研究肌肉和运动能力(MPF)与青光眼发病率之间的关系。方法：2001年4月至2002年3月，共有27,051名年龄在20-87岁之间的无青光眼参与者接受了体能测试。MPF指数是根据握力、垂直跳跃、单腿平衡、前屈和全身反应时间的年龄和性别总分计算出来的。参与者根据强积金指数和每项体能测试被分为四个分位数。参与者被跟踪观察青光眼的发展，青光眼的定义是基于2002年4月至2008年3月期间的年度健康检查中医生诊断的青光眼。使用COX比例风险模型估计青光眼发病率的风险比。结果：在随访期间，303名参与者发展为青光眼。与强积金指数最低组相比，强积金指数最高组发生青光眼的危险比(95%可信区间)为0.6 4(0.46~0.89)(Pfor Trend = .0 0 1)。垂直跳跃和全身反应时间与青光眼的发生有关(趋势 = 分别为.01和P<0.01)。其他体能测试与青光眼发病率无相关性。结论：MPF越高，青光眼发病率越低。
Background: To examine the association between muscular and performance fitness (MPF) and the incidence of glaucoma.Methods: A total of 27,051 glaucoma-free participants aged 20–87 years underwent physical fitness tests between April 2001 and March 2002. The MPF index was calculated using an age- and sex-specific summedz-score from grip strength, vertical jump, single-leg balance, forward bending, and whole-body reaction time. The participants were divided into quartiles according to the MPF index and each physical fitness test. Participants were followed up for the development of glaucoma, which was defined based on physician-diagnosed glaucoma at an annual health examination between April 2002 and March 2008. Hazard ratios for the incidence of glaucoma were estimated using Cox proportional hazards models.Results: During follow-up, 303 participants developed glaucoma. Compared with the lowest MPF index group, hazard ratio (95% confidence interval) of developing glaucoma was 0.64 (0.46–0.89) for the highest MPF index group (Pfor trend = .001). Vertical jump and whole-body reaction time were associated with incident glaucoma (Pfor trend = .01 and <.001, respectively). There were no associations between the other physical fitness tests and the incidence of glaucoma.Conclusion: Higher MPF is associated with lower incidence of glaucoma.