Generation of hiPSTZ16 (ISMMSi003-A) cell line from normal human foreskin fibroblasts.
Generation of hiPSTZ16 (ISMMSi003-A) cell line from normal human foreskin fibroblasts.
复制标题
从正常人包皮成纤维细胞生成 hiPSTZ16 (ISMMSi003-A) 细胞系。
DOI：
10.1016/j.scr.2017.11.019
复制
发表时间：
2018
影响因子：
1.2
通讯作者：
Zwaka,ThomasP
中科院分区：
文献类型：
--
作者：
Dejosez,Marion;Zwaka,ThomasP
将来自商业来源的人包皮成纤维细胞重编程为诱导多能干细胞以建立克隆干细胞系hiPSTZ 16（ISMMSi 003-A）。这些细胞在畸胎瘤测定中显示正常核型和完全分化潜能。所描述的细胞与从正常人包皮成纤维细胞产生的其他iPS细胞系组合提供了有用的资源，以研究下游应用中的来源和重编程方法无关的作用。
Human foreskin fibroblasts from a commercial source were reprogrammed into induced pluripotent stem cells to establish a clonal stem cell line, hiPSTZ16 (ISMMSi003-A). These cells show a normal karyotype and full differentiation potential in teratoma assays. The described cells provide a useful resource in combination with other iPS cell lines generated from normal human foreskin fibroblasts to study source- and reprogramming method-independent effects in downstream applications.