[Epidemiological characteristics and the development of spatiotemporal analysis models on hemorrhagic fever with renal syndrome in China].
[Epidemiological characteristics and the development of spatiotemporal analysis models on hemorrhagic fever with renal syndrome in China].
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DOI：
10.3760/cma.j.cn112338-20191108-00794
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发表时间：
2020-10-10
影响因子：
--
通讯作者：
Liu, K
中科院分区：
文献类型：
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作者：
Chen, J J;Guo, T C;Liu, K
肾综合征出血热（HFRS）是由汉坦病毒（HV）引起的一种自然疫源性鼠传疾病，临床特征为发热、出血、充血、低血压休克和肾损害。人类可通过接触感染鼠的排泄物或分泌物而感染。肾综合征出血热的流行病学特征在人群差异、地域差异和季节变化方面存在显著不同，这些都与宿主动物的栖息地和人类生产活动密切相关。全世界每年报告的肾综合征出血热病例数约为15万至20万例，中国占报告病例总数的70% - 90%，是感染最严重的国家。在本研究中，我们回顾了肾综合征出血热的流行病学特征和影响因素，以及相关生态学研究中使用的模型和方法，以便更好地了解肾综合征出血热传播的时间、区域和人群分布以及潜在影响因素，从而改进该疾病的调查、监测、预防和控制策略。
Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease of natural infectious focus caused by Hantavirus (HV) with clinical characteristics as fever, hemorrhage, hyperemia, hypotensive shock and renal damage. Through contacting the excreta or secretion of infected rats, human may get infected. The epidemiological characteristics of HFRS are significantly different in terms of population differences, geographical heterogeneity and seasonal variation, which are all closely related to the habitat of host animals and human productive activities. The reported number of HFRS is about 150 000 to 200 000 each year worldwide, and China accounted for 70%-90% of the total reported cases standing the most seriously infected country. In this study, we reviewed the epidemiological characteristics and the influencing factors of HFRS as well as the models and methods used in relevant ecological studies, in order to understand the distribution of time, regional and population and potential influencing factors on the transmission of HFRS better, so as to improve the strategies on investigation, monitoring, prevention and control of the diseases.