Aerobic exercise training enhances cerebrovascular pulsatility response to acute aerobic exercise in older adults.
Aerobic exercise training enhances cerebrovascular pulsatility response to acute aerobic exercise in older adults.
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DOI：
10.14814/phy2.13681
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发表时间：
2018-04
影响因子：
2.5
通讯作者：
Maeda S
中科院分区：
文献类型：
--
作者：
Akazawa N;Tanahashi K;Kosaki K;Ra SG;Matsubara T;Choi Y;Zempo-Miyaki A;Maeda S
大脑的低阻力确保了整个收缩期和舒张期的血流强劲，并且容易受到血流脉动的影响。脑搏动增加有助于脑血管疾病的进展。尽管有氧运动会影响血管功能，但人们对运动对老年人大脑搏动指数的影响知之甚少。本研究的目的是调查运动训练对老年人运动后大脑搏动反应的影响。十名健康老年人参加了为期 12 周的运动训练干预。干预前后，我们在基线时通过经颅多普勒方法测量大脑中动脉的搏动指数，并在进行与通气阈值相对应的强度的自行车运动后进行。在运动训练之前，急性自行车运动的大脑搏动反应没有显着变化。然而，干预后，30 分钟的急性自行车运动后，大脑搏动显着下降（P < 0.05）。这项研究表明，在与通气阈值相对应的强度下进行一次急性自行车运动后，大脑搏动指数没有变化，但经过 12 周的运动训练，单次自行车运动后 30 分钟，大脑搏动指数下降。这些结果表明，长期有氧运动训练可能会增强老年人运动后搏动指数的降低。
The brain's low resistance ensures a robust blood flow throughout systole and diastole and is susceptible to flow pulsatility. Increased cerebral pulsatility contributes to the progression of cerebrovascular disease. Although aerobic exercise affects vascular function, little is known about the effect of exercise on the cerebral pulsatility index in older adults. The aim of this study was to investigate the effect of exercise training on the post‐exercise cerebral pulsatility response in older adults. Ten healthy older adults participated in a 12‐week exercise training intervention. Before and after the intervention, we measured the pulsatility index of the middle cerebral artery by means of transcranial Doppler method at baseline and following a cycling exercise bout performed at an intensity corresponding to the ventilatory threshold. Before exercise training, there was no significant change in the cerebral pulsatility response to an acute bout of cycling exercise. However, after the intervention, cerebral pulsatility decreased significantly following 30 min of an acute cycling exercise (P < 0.05). This study demonstrated that cerebral pulsatility index did not change following an acute bout of cycling exercise at an intensity corresponding to ventilatory threshold, but that, after 12 weeks of exercise training, cerebral pulsatility index was reduced at 30 min after a single bout of cycling exercise. These results suggest that long‐term aerobic exercise training may enhance the post‐exercise reduction in pulsatility index in older adults.