Physiological Simulation by Integrating a Circulatory System Model with Beat-by-Beat Hemodynamics
Physiological Simulation by Integrating a Circulatory System Model with Beat-by-Beat Hemodynamics
复制标题
通过将循环系统模型与逐次心跳血流动力学相结合进行生理模拟
DOI：
10.1007/978-3-540-45226-3_53
复制
发表时间：
2003
期刊：
影响因子：
--
通讯作者：
T. Kitamura
中科院分区：
文献类型：
--
作者：
K. Asami;T. Kitamura
本文介绍了一种利用逐拍血流动力学对人体循环系统进行生理模拟的方法。循环系统模型包括神经反射、温度调节、酸碱平衡和O2/CO2平衡等综合生理单元模块中的主要器官和功能。一种逐跳心脏模型，其中相应的电路问题通过数值分析得到解决，从而能够计算流向主要器官的脉动血流。该计算模型融合了不同的生理变化视角，适用于人体不同状态下血液流动的微观评价。
In this paper a physiological simulation method for the human circulatory system with beat-by-beat hemodynamics is described. A circulatory system model includes principal organs and functions in modules of comprehensive physiological units such as nerve reflexes, temperature regulation, acid/base equilibrium, and O2/CO2 balance. A beat-by-beat heart model, in which the corresponding electrical circuit problems are solved by numerical analysis, enables calculation of pulsating blood flow to the major organs. The integration of different perspectives on physiological changes makes this computation model applicable for the microscopic evaluation of blood flow under various states in the human body.