Increased migration levels of bisphenol A from polycarbonate baby bottles after dishwashing, boiling and brushing
Increased migration levels of bisphenol A from polycarbonate baby bottles after dishwashing, boiling and brushing
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DOI：
10.1080/02652030210134236
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发表时间：
2003-07-01
期刊：
影响因子：
--
通讯作者：
Herikstad, H
中科院分区：
文献类型：
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作者：
Brede, C;Fjeldal, P;Herikstad, H
婴儿奶瓶通常是由聚碳酸酯塑料制成的。瓶子中残留的单体双酚A的杂质可能会从塑料瓶迁移到婴儿食品中，从而引起健康问题。之前对新婴儿奶瓶的迁移测试显示，这种物质只有微量迁移水平。在本工作中，聚碳酸酯婴儿奶瓶通过洗碗、煮沸和刷牙的方式进行模拟使用。对新瓶子和旧瓶子进行的迁移测试显示，由于使用，双酚A的迁移显著增加。这一发现可能可以用聚合物降解来解释。建立了固相萃取-气相色谱-质谱法测定200ml水食品模拟物中双酚A的方法。检出限为0.1g L(-1)。12个不同的聚碳酸酯婴儿奶瓶在100℃的热水中灌装1h，新奶瓶的双酚A平均水平为0.23±0.12杯L(-1)，而模拟使用的奶瓶平均双酚A水平分别为8.4±4杯L(-1)(洗51次)和6.7±-4杯L(-1)(洗169次)。这些瓶子释放的双酚A都没有超过欧盟最近制定的临时每日可容忍摄入量(0.01毫克公斤(-1)体重/天)。
Baby bottles are often made of polycarbonate plastic. Impurities remaining in the bottle from the monomer bisphenol A can migrate from the plastic bottles into baby food, thereby causing a health concern. Previous migration testing of new baby bottles showed only trace migration levels of the substance. In the present work, polycarbonate baby bottles were subjected to simulated use by dishwashing, boiling and brushing. Migration testing performed with both new and used bottles revealed a significant increase in migration of bisphenol A due to use. This finding might be explained by polymer degradation. Bisphenol A was determined in 200-ml samples of water food simulant by a method based on solid-phase extraction followed by gas chromatography coupled with mass spectrometry. The detection limit was 0.1 mug l(-1) . Twelve different polycarbonate baby bottles were tested by filling them with hot water (100degreesC) for 1 h. The mean bisphenol A level from new bottles was 0.23 + -0.12 mug l(-1) , while the mean levels from bottles subjected to simulated use were 8.4 + -4 mug l(-1) (dishwashed 51 times) and 6.7 + -4 mug l(-1) (dishwashed 169 times), respectively. None of the bottles released bisphenol A at levels that exceed the recently established provisional tolerable daily intake (0.01 mg kg(-1) body weight/day) in the European Union.