Visualization of protein sequence features using JavaScript and SVG with pViz.js
Visualization of protein sequence features using JavaScript and SVG with pViz.js
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DOI：
10.1093/bioinformatics/btu567
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发表时间：
2014-12-01
期刊：
影响因子：
5.8
通讯作者：
Masselot, Alexandre
中科院分区：
文献类型：
--
作者：
Mukhyala, Kiran;Masselot, Alexandre
PViz.js是一个可视化库，用于在Web浏览器中显示序列特征。通过简单地提供一个数据库及其功能的位置，这个轻量级的、但又是JavaScript的库呈现了一个蛋白质的交互视图。尽管许多网站开发了查看器来显示这些功能，但他们的查看器通常专注于来自特定来源的数据或使用这些查看器中的一些可以调整以适应其他用例的情况不是设计为可重复使用的。PViz使其易于显示为与蛋白质序列对齐的框，具有缩放功能，还包括用于二级结构和翻译修饰的预定义渲染。图书馆的设计就是为了推进这一观点。我们用例子演示了pViz的这些应用：一个带查看器的蛋白质组数据可视化工具，用于显示蛋白质结构上的特征，以及一个用于将EnSembl的Variant_Effect_Predictor工具的结果具体化的工具。
pViz.js is a visualization library for displaying sequence features in a Web browser. By simply providing a and the locations of its features, this lightweight, yet JavaScript library renders an interactive view of the protein Interactive exploration of protein sequence features over the Web is common need in Bioinformatics. Although many Web sites developed viewers to display these features, their are usually focused on data from a specific source or use Some of these viewers can be adapted to fit other use cases are not designed to be reusable. pViz makes it easy to display as boxes aligned to a protein sequence with zooming functionality also includes predefined renderings for secondary structure and translational modifications. The library is designed to further this view. We demonstrate such applications of pViz using examples: a proteomic data visualization tool with an viewer for displaying features on protein structure, and a tool to alize the results of the variant_effect_predictor tool from Ensembl.