Fluorescein angiography versus optical coherence tomography-guided planning for macular laser photocoagulation in diabetic macular edema.
Fluorescein angiography versus optical coherence tomography-guided planning for macular laser photocoagulation in diabetic macular edema.
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DOI：
10.1097/iae.0000000000000120
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发表时间：
2014-08
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影响因子：
--
通讯作者：
Arevalo JF
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作者：
Kozak I;El-Emam SY;Cheng L;Bartsch DU;Chhablani J;Freeman WR;Arevalo JF
比较荧光素血管造影(FA)与光学相干断层扫描(OCT)视网膜厚度图治疗糖尿病黄斑水肿(DME)的激光光凝方案。采用导航激光光凝仪对14只DME患者进行了FA检查。将光学相干断层扫描中心视网膜厚度图导入光凝器，并以相同的放大率对准视网膜。三位视网膜专家分别在FA和OCT图像上以蒙版方式放置激光光斑标记。每个医生放置的斑点在FA和OCT之间以及在医生之间进行了比较。比较同眼行OCT检查时FA上的染料渗漏面积和视网膜中央厚度的增加。FA和OCT模板的平均斑点数分别为36.64和40.61(P=0.0201)。染料渗漏面积平均为7.45mm2，而同眼OCT中央增厚平均面积为10.92mm2(P=0.013)。黄斑光凝的治疗计划存在多样性，在OCT的指导下比FA指导下有放置更多斑点的趋势。一旦有这样的信息，与视网膜对齐的OCT地图的整合可能会对治疗计划产生影响。
To compare laser photocoagulation plans for diabetic macular edema (DME) using fluorescein angiography (FA) versus optical coherence tomography (OCT) thickness map superimposed on the retina. Fourteen eyes with DME undergoing navigated laser photocoagulation with navigated photocoagulator had FA taken using the same instrument. Optical coherence tomography central retinal thickness map was imported to the photocoagulator and with same magnification aligned onto the retina. Three retina specialists placed laser spot marks separately on FA and OCT image in a masked fashion. The spots placed by each physician were compared between FA and OCT and among physicians. The area of dye leakage on FA and increased central retinal thickness on OCT of the same eye were also compared. The average number of spots using FA and OCT template was 36.64 and 40.61, respectively (P = 0.0201). The average area of dye leakage was 7.45 mm2, whereas the average area of increased central retinal thickness on OCT of the same eye was 10.92 mm2 (P = 0.013). There is variability in the treatment planning for macular photocoagulation with a tendency to place more spots when guided by OCT than by FA. Integration of OCT map aligned to the retina may have an impact on treatment plan once such information is available.