The prevalence of methamphetamine and other drug use during pregnancy in Hawaii
The prevalence of methamphetamine and other drug use during pregnancy in Hawaii
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DOI：
10.1177/002204260303300411
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发表时间：
2003-09-01
影响因子：
1.7
通讯作者：
Easa, D
中科院分区：
文献类型：
--
作者：
Derauf, C;Katz, AR;Easa, D
甲基安非他明滥用在夏威夷很流行，但孕妇使用的程度尚不清楚。我们试图确定怀孕期间使用的流行率。我们对1999年11月至12月间连续出生的婴儿进行了横断面研究，确定胎粪中药物代谢物的流行率为脂肪酸乙酯：72例（17.1%）;可替宁：33例（7.7%）;阿片类药物：4例（0.9%）; δ-9四氢大麻醛：1例（0.2%）;甲基苯丙胺：3例（0.7%）。包括仅通过法医检测发现的三个阳性，怀孕期间甲基苯丙胺暴露的总体患病率为1.4%（6/443）。甲基苯丙胺的流行率低于脂肪酸乙酯的流行率（据报告，脂肪酸乙酯是接触乙醇的标志）和可替宁（一种烟草代谢物）。在夏威夷，应该更多地关注怀孕期间的酒精和烟草使用。
Methamphetamine abuse is epidemic in Hawaii, but the extent of use among pregnant women is unknown. We sought to define the prevalence of use during pregnancy. We conducted a cross-sectional study of consecutive births between November and December 1999, and determined that the prevalence of drug metabolites in meconium were fatty acid ethyl esters: 72 (17.1%); cotinine: 33 (7.7%); opiates: 4 (0.9%); delta-9 tetrahydrocannabinal: 1 (0.2%); and methamphetamine: 3 (0.7%). Including three positives discovered solely through forensic testing, the overall prevalence of methamphetamine exposure during pregnancy was 1.4% (6/443). The prevalence of methamphetamine was low compared to the prevalence of fatty acid ethyl esters, reportedly indicative of ethanol exposure, and cotinine, a tobacco metabolite. In Hawaii, more attention should be directed towards alcohol and tobacco use during pregnancy.