Depression involved in self-reported prospective memory problems in survivors of breast cancer who have received chemotherapy

Depression involved in self-reported prospective memory problems in survivors of breast cancer who have received chemotherapy
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接受化疗的乳腺癌幸存者自我报告的前瞻性记忆问题与抑郁症有关

DOI:
10.1097/md.0000000000015301
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发表时间:
2019-04-01
期刊:
影响因子:
1.6
通讯作者:
Cheng, Huaidong
Cheng, Huaidong
中科院分区:
医学4区
文献类型:
--
作者:
Huang, Zhonglian;Zhao, Jingjing;Cheng, Huaidong

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摘要:探讨乳腺癌化疗幸存者抑郁与自我前瞻记忆(SPM)问题的关系。对63例乳腺癌患者进行抑郁自评量表(SDS)和前瞻记忆问卷调查,作为化疗前后广泛神经心理学评估的一部分。比较SDS和SPM的性能,显著性水平设为P < 0.05。与化疗前组比较,SPM评分差异有统计学意义(t = 6.069, P =。在化疗后的乳腺癌患者中。此外,在SPM得分上也存在显著差异(t = - 4.348, P =。化疗后抑郁组与非抑郁组之间的差异。本研究结果提示化疗后乳腺癌幸存者的抑郁可能与化疗诱导的SPM损伤有关。
Abstract To investigate the relationship between depression and the self-reported prospective memory (SPM) problems in breast cancer survivors who have received chemotherapy. Sixty-three breast cancer patients were administered with self-rating depression scale (SDS) and the prospective memory questionnaire as part of extensive neuropsychological assessments before and after chemotherapy. The performance of SDS and SPM were compared, with the level of significance set at P < .05. Compared with the group before chemotherapy, there is a significant difference on the SPM score (t = 6.069, P = .000) in breast cancer patients after chemotherapy. Further, there is also a significant difference on the SPM score (t = −4.348, P = .000) between the patients with and without depression group after chemotherapy. The present result indicated that the depression in breast cancer survivors after chemotherapy may be involved in their chemotherapy-induced SPM impairment.