The parafascicular nucleus relays spinal inputs to the striatum: An electron microscope study in the rat
The parafascicular nucleus relays spinal inputs to the striatum: An electron microscope study in the rat
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DOI：
10.1016/j.neures.2006.05.009
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发表时间：
2006-09-01
影响因子：
2.9
通讯作者：
Tokuno, Hironobu
中科院分区：
文献类型：
--
作者：
Nakamura, Yasuhisa;Otake, Kazuyoshi;Tokuno, Hironobu
在光镜和电镜下观察到大鼠脊髓向纹状体的双突触投射。顺行示踪剂，麦胚凝集素结合辣根过氧化物酶被注射到腹侧灰质的上颈脊髓，和逆行示踪剂，生物素化葡聚糖胺被注射到纹状体的大鼠。然后检查束旁核。一些顺行标记的轴突终末起源于脊髓与逆行标记的束旁核神经元的树突突触，将轴突送到纹状体。我们的结论是，来自脊髓的信息被传递到纹状体，由束旁核神经元中继。(c)2006年Elsevier爱尔兰有限公司和日本神经科学学会。All rights reserved.
A disynaptic projection from the spinal cord to the striatum was observed in the rat light and electron microscopically. An anterograde tracer, wheat germ agglutinin conjugated to horseradish peroxidase was injected into the ventral gray matter of the upper cervical spinal cord, and a retrograde tracer, biotinylated dextran amine was injected into the striatum of a rat. Then the parafascicular nucleus was examined. Some anterogradely labeled axon terminals originating in the spinal cord were observed to synapse with retrogradely labeled dendrites of parafascicular nucleus neurons which sent axons to the striatum. We concluded that information from the spinal cord was transmitted to the striatum, being relayed by parafascicular nucleus neurons. (c) 2006 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.