Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences
Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences
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DOI：
10.1093/nar/gkg786
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发表时间：
2003-10-01
影响因子：
14.9
通讯作者：
Lee, C
中科院分区：
文献类型：
--
作者：
Xu, Q;Lee, C
我们在这里报告了一个全基因组分析的选择性剪接在200万人类表达序列标签（EST），以确定剪接形式，在肿瘤中相对于正常组织上调。我们发现了有力的证据（P
We report here a genome-wide analysis of alternative splicing in 2 million human expressed sequence tags (ESTs), to identify splice forms that are up-regulated in tumors relative to normal tissues. We found strong evidence (P