Functional Magnetic Resonance Imaging (fmri) Was Used to Investigate the Neural Substrates of Component Processes in Verbal Working Memory. Based on Behavioral Research Using
Functional Magnetic Resonance Imaging (fmri) Was Used to Investigate the Neural Substrates of Component Processes in Verbal Working Memory. Based on Behavioral Research Using
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操纵的言语刺激类型分离的存储，排练，和执行组件的言语工作记忆，我们设计了一个延迟的系列回忆任务，要求受试者编码，保持，并公开回忆集的言语项目，语音相似性，发音长度，和词汇状态进行了操纵。通过使用一个任务与时间延长试验，我们能够利用功能磁共振成像提供的时间分辨率，部分隔离神经的贡献，编码，维护和检索阶段的任务性能。几个区域通常与维护，包括辅助运动，运动前区，和下额叶区，被发现活跃在所有三个试验阶段。此外，我们发现，左下额叶和辅助运动区域显示的模式的刺激和时间敏感性牵连他们在发音排练的不同方面，而没有区域显示的模式的敏感性与语音存储的作用一致。区域调制任务难度进一步调查作为执行处理的措施。我们解释我们的研究结果，因为它们涉及到概念的认知结构的基础上的口头工作记忆的表现。
manipulations of verbal stimulus type to dissociate storage, rehearsal, and executive components of verbal working memory, we designed a delayed serial recall task requiring subjects to encode, maintain, and overtly recall sets of verbal items for which phonological similarity, articulatory length, and lexical status were manipulated. By using a task with temporally extended trials, we were able to exploit the temporal resolution afforded by fMRI to partially isolate neural contributions to encoding, maintenance, and retrieval stages of task performance. Several regions commonly associated with maintenance, including supplementary motor, premotor, and inferior frontal areas, were found to be active across all three trial stages. Additionally, we found that left inferior frontal and supplementary motor regions showed patterns of stimulus and temporal sensitivity implicating them in distinct aspects of articulatory rehearsal, while no regions showed a pattern of sensitivity consistent with a role in phonological storage. Regional modulation by task difficulty was further investigated as a measure of executive processing. We interpret our findings as they relate to notions about the cognitive architecture underlying verbal working memory performance.