Fluorescence and biological stabilization of phosphorus-functionalized mesoporous silica nanospheres modified with a bis(8-hydroxyquinoline) zinc complex
Fluorescence and biological stabilization of phosphorus-functionalized mesoporous silica nanospheres modified with a bis(8-hydroxyquinoline) zinc complex
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双（8-羟基喹啉）锌配合物修饰的磷功能化介孔二氧化硅纳米球的荧光和生物稳定性
DOI：
10.1039/d1ma00636c
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发表时间：
2021
影响因子：
5
通讯作者：
Tagaya Motohiro
中科院分区：
文献类型：
--
作者：
Saito Norio;Noda Daichi;Shang Yucheng;Yamada Shota;Tagaya Motohiro
采用8-羟基喹啉锌（Znq 2）对介孔二氧化硅（PMPS）纳米球进行表面修饰，制备了具有绿色荧光的PMPS纳米球。模拟体液浸泡试验和随后的气体吸附测量表明，Znq 2修饰可以显着抑制纳米球的生物降解。本研究确立Znq 2作为一种新型的和潜在的介孔二氧化硅的表面改性剂，并表明，有效的表面设计的主机将允许开发潜在的功能性的改性剂。
Green-emitting phosphorus-functionalized mesoporous silica (PMPS) nanospheres were fabricated by modifying their surfaces with (8-hydroxyquinoline) zinc (Znq2). A simulated body fluid soaking test and subsequent gas-adsorption measurements revealed that Znq2-modification could dramatically suppress the biodegradation of the nanospheres. This study establishes Znq2 as a novel and potential surface modifier of mesoporous silicas and demonstrates that effective surface design of the hosts will allow the exploitation of potential functionalities of the modifier.